| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10021009 | HBV | ENSG00000005156.12 | protein_coding | LIG3 | No | No | 3980 | P49916 |
| TVIS20037398 | HPV | ENSG00000005156.12 | protein_coding | LIG3 | No | No | 3980 | P49916 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | LIG3 |
|---|---|
| DrugBank ID | DB00290 |
| Drug Name | Bleomycin |
| Target ID | BE0000167 |
| UniProt ID | P49916 |
| Regulation Type | inhibitor |
| PubMed IDs | 17202402 |
| Citations | Rose JL, Reeves KC, Likhotvorik RI, Hoyt DG: Base excision repair proteins are required for integrin-mediated suppression of bleomycin-induced DNA breakage in murine lung endothelial cells. J Pharmacol Exp Ther. 2007 Apr;321(1):318-26. Epub 2007 Jan 3. |
| Groups | Approved; Investigational |
| Direct Classification | Hybrid glycopeptides |
| SMILES | [H][C@](C)(NC(=O)[C@@]([H])(NC(=O)C1=NC(=NC(N)=C1C)[C@H](CC(N)=O)NC[C@H](N)C(N)=O)[C@@]([H])(OC1OC(CO)C(O)C(O)C1OC1OC(CO)C(O)C(OC(N)=O)C1O)C1=CNC=N1)[C@@H](O)[C@H](C)C(=O)N[C@]([H])(C(=O)NCCC1=NC(=CS1)C1=NC(=CS1)C(=O)NCCC[S+](C)C)[C@@]([H])(C)O |
| Pathways | |
| PharmGKB | PA448645 |
| ChEMBL | CHEMBL403664 |
