| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30074652 | HIV | ENSG00000226979.9 | protein_coding | LTA | No | No | 4049 | P01374 Q5STV3 |
| TVIS44031096 | HTLV-1 | ENSG00000226979.9 | protein_coding | LTA | No | No | 4049 | P01374 Q5STV3 |
| TVIS44025701 | HTLV-1 | ENSG00000226979.9 | protein_coding | LTA | No | No | 4049 | P01374 Q5STV3 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | LTA |
|---|---|
| DrugBank ID | DB00005 |
| Drug Name | Etanercept |
| Target ID | BE0001087 |
| UniProt ID | P01374 |
| Regulation Type | antibody |
| PubMed IDs | 11302411; 15005015; 15033655 |
| Citations | Johnson CJ, Reilly KM, Murray KM: Etanercept in juvenile rheumatoid arthritis. Ann Pharmacother. 2001 Apr;35(4):464-71.@@Gudbrandsdottir S, Larsen R, Sorensen LK, Nielsen S, Hansen MB, Svenson M, Bendtzen K, Muller K: TNF and LT binding capacities in the plasma of arthritis patients: effect of etanercept treatment in juvenile idiopathic arthritis. Clin Exp Rheumatol. 2004 Jan-Feb;22(1):118-24.@@Buch MH, Conaghan PG, Quinn MA, Bingham SJ, Veale D, Emery P: True infliximab resistance in rheumatoid arthritis: a role for lymphotoxin alpha? Ann Rheum Dis. 2004 Oct;63(10):1344-6. Epub 2004 Mar 19. |
| Groups | Approved; Investigational |
| Direct Classification | Peptides |
| SMILES | |
| Pathways | |
| PharmGKB | PA449515 |
| ChEMBL | CHEMBL1201572 |
