Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS42000435EBVENSG00000133800.9protein_codingLYVE1NoNo10894Q9Y5Y7
TVIS10045926HBVENSG00000133800.9protein_codingLYVE1NoNo10894Q9Y5Y7
TVIS30080077HIVENSG00000133800.9protein_codingLYVE1NoNo10894Q9Y5Y7
TVIS20009914HPVENSG00000133800.9protein_codingLYVE1NoNo10894Q9Y5Y7
TVIS20040374HPVENSG00000133800.9protein_codingLYVE1NoNo10894Q9Y5Y7
TVIS20049463HPVENSG00000133800.9protein_codingLYVE1NoNo10894Q9Y5Y7
TCGA Plot Options
Drug Information
GeneLYVE1
DrugBank IDDB08818
Drug NameHyaluronic acid
Target IDBE0010044
UniProt IDQ9Y5Y7
Regulation Type
PubMed IDs31294035; 26823460
CitationsGupta RC, Lall R, Srivastava A, Sinha A: Hyaluronic Acid: Molecular Mechanisms and Therapeutic Trajectory. Front Vet Sci. 2019 Jun 25;6:192. doi: 10.3389/fvets.2019.00192. eCollection 2019.@@Lawrance W, Banerji S, Day AJ, Bhattacharjee S, Jackson DG: Binding of Hyaluronan to the Native Lymphatic Vessel Endothelial Receptor LYVE-1 Is Critically Dependent on Receptor Clustering and Hyaluronan Organization. J Biol Chem. 2016 Apr 8;291(15):8014-30. doi: 10.1074/jbc.M115.708305. Epub 2016 Jan 28.
GroupsApproved; Vet_approved
Direct ClassificationAcylaminosugars
SMILESCC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)C1O[C@@H]1O[C@@H]([C@@H](O[C@@H]2O[C@H](CO)[C@@H](O)C(O[C@@H]3O[C@@H]([C@@H](O)[C@H](O)[C@H]3O)C(O)=O)[C@H]2NC(C)=O)[C@H](O)[C@H]1O)C(O)=O
Pathways
PharmGKBPA165958431
ChEMBL