| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS42000059 | EBV | ENSG00000151376.19 | protein_coding | ME3 | No | No | 10873 | Q16798 Q6TCH8 |
| TVIS10006111 | HBV | ENSG00000151376.19 | protein_coding | ME3 | No | No | 10873 | Q16798 Q6TCH8 |
| TVIS10006112 | HBV | ENSG00000151376.19 | protein_coding | ME3 | No | No | 10873 | Q16798 Q6TCH8 |
| TVIS10004088 | HBV | ENSG00000151376.19 | protein_coding | ME3 | No | No | 10873 | Q16798 Q6TCH8 |
| TVIS10026676 | HBV | ENSG00000151376.19 | protein_coding | ME3 | No | No | 10873 | Q16798 Q6TCH8 |
| TVIS10042944 | HBV | ENSG00000151376.19 | protein_coding | ME3 | No | No | 10873 | Q16798 Q6TCH8 |
| TVIS10044213 | HBV | ENSG00000151376.19 | protein_coding | ME3 | No | No | 10873 | Q16798 Q6TCH8 |
| TVIS10050841 | HBV | ENSG00000151376.19 | protein_coding | ME3 | No | No | 10873 | Q16798 Q6TCH8 |
| TVIS10052164 | HBV | ENSG00000151376.19 | protein_coding | ME3 | No | No | 10873 | Q16798 Q6TCH8 |
| TVIS10050385 | HBV | ENSG00000151376.19 | protein_coding | ME3 | No | No | 10873 | Q16798 Q6TCH8 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | ME3 |
|---|---|
| DrugBank ID | DB00157 |
| Drug Name | NADH |
| Target ID | BE0000328 |
| UniProt ID | Q16798 |
| Regulation Type | |
| PubMed IDs | 16740313; 17080607; 17603759 |
| Citations | Luo C, Wang X, Long J, Liu J: An NADH-tetrazolium-coupled sensitive assay for malate dehydrogenase in mitochondria and crude tissue homogenates. J Biochem Biophys Methods. 2006 Aug 31;68(2):101-11. Epub 2006 Apr 26.@@Wei H, Dhanaraj AL, Arora R, Rowland LJ, Fu Y, Sun L: Identification of cold acclimation-responsive Rhododendron genes for lipid metabolism, membrane transport and lignin biosynthesis: importance of moderately abundant ESTs in genomic studies. Plant Cell Environ. 2006 Apr;29(4):558-70.@@Rzem R, Vincent MF, Van Schaftingen E, Veiga-da-Cunha M: L-2-hydroxyglutaric aciduria, a defect of metabolite repair. J Inherit Metab Dis. 2007 Oct;30(5):681-9. Epub 2007 Jun 21. |
| Groups | Approved; Nutraceutical |
| Direct Classification | (5'->5')-dinucleotides |
| SMILES | NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O |
| Pathways | Ethylmalonic Encephalopathy; 3-Methylglutaconic Aciduria Type III; Short-Chain Acyl-CoA Dehydrogenase Deficiency (SCAD Deficiency); Caffeine Metabolism; Fructose and Mannose Degradation; Isovaleric Aciduria; Lysine Degradation; Methylmalonic Aciduria Due to Cobalamin-Related Disorders; Glycerol Phosphate Shuttle; Zellweger Syndrome; Propionic Acidemia; Glycolysis; Xanthine Dehydrogenase Deficiency (Xanthinuria); S-Adenosylhomocysteine (SAH) Hydrolase Deficiency; Tryptophan Metabolism; Glutaric Aciduria Type I; 3-Methylcrotonyl-CoA Carboxylase Deficiency Type I; Glycine N-Methyltransferase Deficiency; Dimethylglycine Dehydrogenase Deficiency; Androgen and Estrogen Metabolism; Nucleotide Sugars Metabolism; 3-Methylglutaconic Aciduria Type IV; Dihydropyrimidine Dehydrogenase Deficiency (DHPD); Malate-Aspartate Shuttle; Folate Metabolism; Valine, Leucine, and Isoleucine Degradation; Maple Syrup Urine Disease; Glycerol Kinase Deficiency; Adenylosuccinate Lyase Deficiency; Cysteine Metabolism |
| PharmGKB | PA164755085 |
| ChEMBL | CHEMBL1234616 |
