Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10010882HBVENSG00000105976.16protein_codingMETYesNo4233E6Y365
P08581
TVIS30067833HIVENSG00000105976.16protein_codingMETYesNo4233E6Y365
P08581
TVIS20012857HPVENSG00000105976.16protein_codingMETYesNo4233E6Y365
P08581
TVIS20062294HPVENSG00000105976.16protein_codingMETYesNo4233E6Y365
P08581
TVIS20023366HPVENSG00000105976.16protein_codingMETYesNo4233E6Y365
P08581
TVIS20022730HPVENSG00000105976.16protein_codingMETYesNo4233E6Y365
P08581
TVIS20061784HPVENSG00000105976.16protein_codingMETYesNo4233E6Y365
P08581
TVIS44016703HTLV-1ENSG00000105976.16protein_codingMETYesNo4233E6Y365
P08581
TVIS44049057HTLV-1ENSG00000105976.16protein_codingMETYesNo4233E6Y365
P08581
TCGA Plot Options
Drug Information
GeneMET
DrugBank IDDB01268
Drug NameSunitinib
Target IDBE0000915
UniProt IDP08581
Regulation Typeinhibitor
PubMed IDs30658233
CitationsIbrahim HS, Albakri ME, Mahmoud WR, Allam HA, Reda AM, Abdel-Aziz HA: Synthesis and biological evaluation of some novel thiobenzimidazole derivatives as anti-renal cancer agents through inhibition of c-MET kinase. Bioorg Chem. 2019 Apr;85:337-348. doi: 10.1016/j.bioorg.2019.01.006. Epub 2019 Jan 8.
GroupsApproved; Investigational
Direct ClassificationIndolines
SMILESCCN(CC)CCNC(=O)C1=C(C)NC(C=C2/C(=O)NC3=C2C=C(F)C=C3)=C1C
Pathways
PharmGKBPA162372840
ChEMBLCHEMBL535