| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10033497 | HBV | ENSG00000075643.6 | protein_coding | MOCOS | No | No | 55034 | Q96EN8 |
| TVIS10050803 | HBV | ENSG00000075643.6 | protein_coding | MOCOS | No | No | 55034 | Q96EN8 |
| TVIS30077104 | HIV | ENSG00000075643.6 | protein_coding | MOCOS | No | No | 55034 | Q96EN8 |
| TVIS20014728 | HPV | ENSG00000075643.6 | protein_coding | MOCOS | No | No | 55034 | Q96EN8 |
| TVIS20014729 | HPV | ENSG00000075643.6 | protein_coding | MOCOS | No | No | 55034 | Q96EN8 |
| TVIS20014736 | HPV | ENSG00000075643.6 | protein_coding | MOCOS | No | No | 55034 | Q96EN8 |
| TVIS20014737 | HPV | ENSG00000075643.6 | protein_coding | MOCOS | No | No | 55034 | Q96EN8 |
| TVIS20014738 | HPV | ENSG00000075643.6 | protein_coding | MOCOS | No | No | 55034 | Q96EN8 |
| TVIS20014739 | HPV | ENSG00000075643.6 | protein_coding | MOCOS | No | No | 55034 | Q96EN8 |
| TVIS44021216 | HTLV-1 | ENSG00000075643.6 | protein_coding | MOCOS | No | No | 55034 | Q96EN8 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | MOCOS |
|---|---|
| DrugBank ID | DB00114 |
| Drug Name | Pyridoxal phosphate |
| Target ID | BE0002167 |
| UniProt ID | Q96EN8 |
| Regulation Type | cofactor |
| PubMed IDs | 15561708; 16784786; 11886751; 11553608 |
| Citations | Heidenreich T, Wollers S, Mendel RR, Bittner F: Characterization of the NifS-like domain of ABA3 from Arabidopsis thaliana provides insight into the mechanism of molybdenum cofactor sulfuration. J Biol Chem. 2005 Feb 11;280(6):4213-8. Epub 2004 Nov 22.@@Mendel RR, Bittner F: Cell biology of molybdenum. Biochim Biophys Acta. 2006 Jul;1763(7):621-35. Epub 2006 May 12.@@Anantharaman V, Aravind L: MOSC domains: ancient, predicted sulfur-carrier domains, present in diverse metal-sulfur cluster biosynthesis proteins including Molybdenum cofactor sulfurases. FEMS Microbiol Lett. 2002 Jan 22;207(1):55-61.@@Bittner F, Oreb M, Mendel RR: ABA3 is a molybdenum cofactor sulfurase required for activation of aldehyde oxidase and xanthine dehydrogenase in Arabidopsis thaliana. J Biol Chem. 2001 Nov 2;276(44):40381-4. Epub 2001 Sep 11. |
| Groups | Approved; Investigational; Nutraceutical |
| Direct Classification | Pyridoxals and derivatives |
| SMILES | CC1=NC=C(COP(O)(O)=O)C(C=O)=C1O |
| Pathways | Histidinemia; 3-Methylglutaconic Aciduria Type I; Guanidinoacetate Methyltransferase Deficiency (GAMT Deficiency); beta-Ketothiolase Deficiency; Tyrosine Metabolism; Disulfiram Action Pathway; Hyperprolinemia Type II; Glutamate Metabolism; Argininosuccinic Aciduria; Tyrosinemia Type I; Hyperinsulinism-Hyperammonemia Syndrome; Porphyrin Metabolism; 2-Methyl-3-hydroxybutryl-CoA Dehydrogenase Deficiency; Glutaric Aciduria Type I; Propanoate Metabolism; Taurine and Hypotaurine Metabolism; Catecholamine Biosynthesis; Glycine and Serine Metabolism; Carnitine Synthesis; Tyrosinemia Type 3 (TYRO3); Selenoamino Acid Metabolism; Carbamoyl Phosphate Synthetase Deficiency; Hyperprolinemia Type I; Saccharopinuria/Hyperlysinemia II; Histidine Metabolism; Cystathionine beta-Synthase Deficiency; Arginine and Proline Metabolism; Starch and Sucrose Metabolism; Globoid Cell Leukodystrophy; Ammonia Recycling |
| PharmGKB | PA164749650 |
| ChEMBL | CHEMBL82202 |
