| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10024786 | HBV | ENSG00000065911.13 | protein_coding | MTHFD2 | Yes | No | 10797 | P13995 |
| TVIS10028552 | HBV | ENSG00000065911.13 | protein_coding | MTHFD2 | Yes | No | 10797 | P13995 |
| TVIS30007704 | HIV | ENSG00000065911.13 | protein_coding | MTHFD2 | Yes | No | 10797 | P13995 |
| TVIS30007705 | HIV | ENSG00000065911.13 | protein_coding | MTHFD2 | Yes | No | 10797 | P13995 |
| TVIS30050669 | HIV | ENSG00000065911.13 | protein_coding | MTHFD2 | Yes | No | 10797 | P13995 |
| TVIS30050670 | HIV | ENSG00000065911.13 | protein_coding | MTHFD2 | Yes | No | 10797 | P13995 |
| TVIS30050671 | HIV | ENSG00000065911.13 | protein_coding | MTHFD2 | Yes | No | 10797 | P13995 |
| TVIS30050672 | HIV | ENSG00000065911.13 | protein_coding | MTHFD2 | Yes | No | 10797 | P13995 |
| TVIS30050673 | HIV | ENSG00000065911.13 | protein_coding | MTHFD2 | Yes | No | 10797 | P13995 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | MTHFD2 |
|---|---|
| DrugBank ID | DB00116 |
| Drug Name | Tetrahydrofolic acid |
| Target ID | BE0000268 |
| UniProt ID | P13995 |
| Regulation Type | cofactor |
| PubMed IDs | 12949177 |
| Citations | Salmassi TM, Leadbetter JR: Analysis of genes of tetrahydrofolate-dependent metabolism from cultivated spirochaetes and the gut community of the termite Zootermopsis angusticollis. Microbiology. 2003 Sep;149(Pt 9):2529-37. |
| Groups | Nutraceutical |
| Direct Classification | Glutamic acid and derivatives |
| SMILES | NC1=NC(=O)C2=C(NCC(CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)N2)N1 |
| Pathways | Histidinemia; Lesch-Nyhan Syndrome (LNS); Molybdenum Cofactor Deficiency; Azathioprine Action Pathway; AICA-Ribosiduria; Purine Nucleoside Phosphorylase Deficiency; Methionine Adenosyltransferase Deficiency; Folate Malabsorption, Hereditary; Adenine Phosphoribosyltransferase Deficiency (APRT); Thioguanine Action Pathway; Mercaptopurine Action Pathway; Non-Ketotic Hyperglycinemia; Methotrexate Action Pathway; Betaine Metabolism; S-Adenosylhomocysteine (SAH) Hydrolase Deficiency; Glycine and Serine Metabolism; Adenosine Deaminase Deficiency; Xanthinuria Type II; Methionine Metabolism; Dihydropyrimidine Dehydrogenase Deficiency (DHPD); Histidine Metabolism; Cystathionine beta-Synthase Deficiency; Folate Metabolism; Sarcosine Oncometabolite Pathway; Sarcosinemia; Methylenetetrahydrofolate Reductase Deficiency (MTHFRD); Purine Metabolism; Gout or Kelley-Seegmiller Syndrome; Adenylosuccinate Lyase Deficiency; Ammonia Recycling |
| PharmGKB | PA164745110 |
| ChEMBL | CHEMBL2021342 |
