| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30006048 | HIV | ENSG00000139180.11 | protein_coding | NDUFA9 | No | No | 4704 | Q16795 |
| TVIS30031847 | HIV | ENSG00000139180.11 | protein_coding | NDUFA9 | No | No | 4704 | Q16795 |
| TVIS30031848 | HIV | ENSG00000139180.11 | protein_coding | NDUFA9 | No | No | 4704 | Q16795 |
| TVIS30031849 | HIV | ENSG00000139180.11 | protein_coding | NDUFA9 | No | No | 4704 | Q16795 |
| TVIS30031850 | HIV | ENSG00000139180.11 | protein_coding | NDUFA9 | No | No | 4704 | Q16795 |
| TVIS30031851 | HIV | ENSG00000139180.11 | protein_coding | NDUFA9 | No | No | 4704 | Q16795 |
| TVIS44017494 | HTLV-1 | ENSG00000139180.11 | protein_coding | NDUFA9 | No | No | 4704 | Q16795 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | NDUFA9 |
|---|---|
| DrugBank ID | DB00157 |
| Drug Name | NADH |
| Target ID | BE0000305 |
| UniProt ID | Q16795 |
| Regulation Type | |
| PubMed IDs | 17323923; 17132781; 17260964; 17499024; 17530440 |
| Citations | Barker CD, Reda T, Hirst J: The flavoprotein subcomplex of complex I (NADH:ubiquinone oxidoreductase) from bovine heart mitochondria: insights into the mechanisms of NADH oxidation and NAD+ reduction from protein film voltammetry. Biochemistry. 2007 Mar 20;46(11):3454-64. Epub 2007 Feb 27.@@Balaban RS: Maintenance of the metabolic homeostasis of the heart: developing a systems analysis approach. Ann N Y Acad Sci. 2006 Oct;1080:140-53.@@Matsuzaki S, Szweda LI: Inhibition of complex I by Ca2+ reduces electron transport activity and the rate of superoxide anion production in cardiac submitochondrial particles. Biochemistry. 2007 Feb 6;46(5):1350-7.@@Fisher N, Bray PG, Ward SA, Biagini GA: The malaria parasite type II NADH:quinone oxidoreductase: an alternative enzyme for an alternative lifestyle. Trends Parasitol. 2007 Jul;23(7):305-10. Epub 2007 May 10.@@Liu Y, Qiao DR, Zheng HB, Dai XL, Bai LH, Zeng J, Cao Y: Cloning and sequence analysis of the gene encoding 19-kD subunit of Complex I from Dunaliella salina. Mol Biol Rep. 2008 Sep;35(3):397-403. Epub 2007 May 26. |
| Groups | Approved; Nutraceutical |
| Direct Classification | (5'->5')-dinucleotides |
| SMILES | NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O |
| Pathways | Ethylmalonic Encephalopathy; 3-Methylglutaconic Aciduria Type III; Short-Chain Acyl-CoA Dehydrogenase Deficiency (SCAD Deficiency); Caffeine Metabolism; Fructose and Mannose Degradation; Isovaleric Aciduria; Lysine Degradation; Methylmalonic Aciduria Due to Cobalamin-Related Disorders; Glycerol Phosphate Shuttle; Zellweger Syndrome; Propionic Acidemia; Glycolysis; Xanthine Dehydrogenase Deficiency (Xanthinuria); S-Adenosylhomocysteine (SAH) Hydrolase Deficiency; Tryptophan Metabolism; Glutaric Aciduria Type I; 3-Methylcrotonyl-CoA Carboxylase Deficiency Type I; Glycine N-Methyltransferase Deficiency; Dimethylglycine Dehydrogenase Deficiency; Androgen and Estrogen Metabolism; Nucleotide Sugars Metabolism; 3-Methylglutaconic Aciduria Type IV; Dihydropyrimidine Dehydrogenase Deficiency (DHPD); Malate-Aspartate Shuttle; Folate Metabolism; Valine, Leucine, and Isoleucine Degradation; Maple Syrup Urine Disease; Glycerol Kinase Deficiency; Adenylosuccinate Lyase Deficiency; Cysteine Metabolism |
| PharmGKB | PA164755085 |
| ChEMBL | CHEMBL1234616 |
