| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30080068 | HIV | ENSG00000134259.6 | protein_coding | NGF | No | No | 4803 | P01138 |
| TVIS20066036 | HPV | ENSG00000134259.6 | protein_coding | NGF | No | No | 4803 | P01138 |
| TVIS44024356 | HTLV-1 | ENSG00000134259.6 | protein_coding | NGF | No | No | 4803 | P01138 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | NGF |
|---|---|
| DrugBank ID | DB01407 |
| Drug Name | Clenbuterol |
| Target ID | BE0001094 |
| UniProt ID | P01138 |
| Regulation Type | stimulator |
| PubMed IDs | 10403429; 10525174; 10637819; 11146120; 11221812 |
| Citations | Culmsee C, Semkova I, Krieglstein J: NGF mediates the neuroprotective effect of the beta2-adrenoceptor agonist clenbuterol in vitro and in vivo: evidence from an NGF-antisense study. Neurochem Int. 1999 Jul;35(1):47-57.@@Semkova I, Krieglstein J: Neuroprotection mediated via neurotrophic factors and induction of neurotrophic factors. Brain Res Brain Res Rev. 1999 Aug;30(2):176-88.@@Puls I, Beck M, Giess R, Magnus T, Ochs G, Toyka KV: [Clenbuterol in amyotrophic lateral sclerosis. No indication for a positive effect]. Nervenarzt. 1999 Dec;70(12):1112-5.@@Samina Riaz S, Tomlinson DR: Pharmacological modulation of nerve growth factor synthesis: a mechanistic comparison of vitamin D receptor and beta(2)-adrenoceptor agonists. Brain Res Mol Brain Res. 2000 Dec 28;85(1-2):179-88.@@Riaz SS, Tomlinson DR: Clenbuterol stimulates neurotrophic support in streptozotocin-diabetic rats. Diabetes Obes Metab. 1999 Jan;1(1):43-51. |
| Groups | Approved; Investigational; Vet_approved |
| Direct Classification | Dichlorobenzenes |
| SMILES | CC(C)(C)NCC(O)C1=CC(Cl)=C(N)C(Cl)=C1 |
| Pathways | |
| PharmGKB | PA164745640 |
| ChEMBL | CHEMBL49080 |
