| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20012580 | HPV | ENSG00000166741.9 | protein_coding | NNMT | No | No | 4837 | P40261 Q6FH49 |
| TVIS44026527 | HTLV-1 | ENSG00000166741.9 | protein_coding | NNMT | No | No | 4837 | P40261 Q6FH49 |
| TVIS44013559 | HTLV-1 | ENSG00000166741.9 | protein_coding | NNMT | No | No | 4837 | P40261 Q6FH49 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | NNMT |
|---|---|
| DrugBank ID | DB00627 |
| Drug Name | Niacin |
| Target ID | BE0000783 |
| UniProt ID | P40261 |
| Regulation Type | binder |
| PubMed IDs | 17139284; 17016423; 18996527 |
| Citations | Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Riederer M, Erwa W, Zimmermann R, Frank S, Zechner R: Adipose tissue as a source of nicotinamide N-methyltransferase and homocysteine. Atherosclerosis. 2009 Jun;204(2):412-7. doi: 10.1016/j.atherosclerosis.2008.09.015. Epub 2008 Sep 27. |
| Groups | Approved; Investigational; Nutraceutical |
| Direct Classification | Pyridinecarboxylic acids |
| SMILES | OC(=O)C1=CN=CC=C1 |
| Pathways | Nicotinate and Nicotinamide Metabolism |
| PharmGKB | PA450617 |
| ChEMBL | CHEMBL573 |
