| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10057268 | HBV | ENSG00000169006.7 | protein_coding | NTSR2 | No | No | 23620 | O95665 |
| TVIS10057269 | HBV | ENSG00000169006.7 | protein_coding | NTSR2 | No | No | 23620 | O95665 |
| TVIS44018754 | HTLV-1 | ENSG00000169006.7 | protein_coding | NTSR2 | No | No | 23620 | O95665 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | NTSR2 |
|---|---|
| DrugBank ID | DB01106 |
| Drug Name | Levocabastine |
| Target ID | BE0000464 |
| UniProt ID | O95665 |
| Regulation Type | partial antagonist |
| PubMed IDs | 11723247; 8647296; 9080465 |
| Citations | Richard F, Barroso S, Martinez J, Labbe-Jullie C, Kitabgi P: Agonism, inverse agonism, and neutral antagonism at the constitutively active human neurotensin receptor 2. Mol Pharmacol. 2001 Dec;60(6):1392-8.@@Chalon P, Vita N, Kaghad M, Guillemot M, Bonnin J, Delpech B, Le Fur G, Ferrara P, Caput D: Molecular cloning of a levocabastine-sensitive neurotensin binding site. FEBS Lett. 1996 May 20;386(2-3):91-4.@@Botto JM, Guillemare E, Vincent JP, Mazella J: Effects of SR 48692 on neurotensin-induced calcium-activated chloride currents in the Xenopus oocyte expression system: agonist-like activity on the levocabastine-sensitive neurotensin receptor and absence of antagonist effect on the levocabastine insensitive neurotensin receptor. Neurosci Lett. 1997 Feb 28;223(3):193-6. |
| Groups | Approved; Investigational |
| Direct Classification | Phenylpiperidines |
| SMILES | C[C@@H]1CN(CC[C@]1(C(O)=O)C1=CC=CC=C1)[C@H]1CC[C@](CC1)(C#N)C1=CC=C(F)C=C1 |
| Pathways | Levocabastine H1-Antihistamine Action |
| PharmGKB | PA164742988 |
| ChEMBL | CHEMBL1615438 |
