| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30047270 | HIV | ENSG00000104904.13 | protein_coding | OAZ1 | No | No | 4946 | J3QQY4 P54368 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | OAZ1 |
|---|---|
| DrugBank ID | DB00129 |
| Drug Name | Ornithine |
| Target ID | BE0000371 |
| UniProt ID | P54368 |
| Regulation Type | |
| PubMed IDs | 16916800; 16354653; 15009201 |
| Citations | Lopez-Contreras AJ, Lopez-Garcia C, Jimenez-Cervantes C, Cremades A, Penafiel R: Mouse ornithine decarboxylase-like gene encodes an antizyme inhibitor devoid of ornithine and arginine decarboxylating activity. J Biol Chem. 2006 Oct 13;281(41):30896-906. Epub 2006 Aug 17.@@Yamaguchi Y, Takatsuka Y, Matsufuji S, Murakami Y, Kamio Y: Characterization of a counterpart to Mammalian ornithine decarboxylase antizyme in prokaryotes. J Biol Chem. 2006 Feb 17;281(7):3995-4001. Epub 2005 Dec 14.@@Janne J, Alhonen L, Pietila M, Keinanen TA: Genetic approaches to the cellular functions of polyamines in mammals. Eur J Biochem. 2004 Mar;271(5):877-94. |
| Groups | Approved; Nutraceutical |
| Direct Classification | L-alpha-amino acids |
| SMILES | NCCC[C@H](N)C(O)=O |
| Pathways | Citrullinemia Type I; Guanidinoacetate Methyltransferase Deficiency (GAMT Deficiency); Argininemia; Hyperornithinemia with Gyrate Atrophy (HOGA); Spermidine and Spermine Biosynthesis; Hyperprolinemia Type II; Argininosuccinic Aciduria; L-Arginine:Glycine Amidinotransferase Deficiency; Hyperornithinemia-Hyperammonemia-Homocitrullinuria [HHH-syndrome]; Arginine: Glycine Amidinotransferase Deficiency (AGAT Deficiency); Prolidase Deficiency (PD); Creatine Deficiency, Guanidinoacetate Methyltransferase Deficiency; Carbamoyl Phosphate Synthetase Deficiency; Ornithine Aminotransferase Deficiency (OAT Deficiency); Hyperprolinemia Type I; Arginine and Proline Metabolism; Ornithine Transcarbamylase Deficiency (OTC Deficiency); Prolinemia Type II; Urea Cycle |
| PharmGKB | PA164783814 |
| ChEMBL | CHEMBL446143 |
