Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10007544HBVENSG00000135124.16protein_codingP2RX4NoNo5025Q99571
TVIS44004599HTLV-1ENSG00000135124.16protein_codingP2RX4NoNo5025Q99571
TCGA Plot Options
Drug Information
GeneP2RX4
DrugBank IDDB09119
Drug NameEslicarbazepine acetate
Target IDBE0005793
UniProt IDQ99571
Regulation Typeantagonist
PubMed IDs24411477
CitationsTian M, Abdelrahman A, Weinhausen S, Hinz S, Weyer S, Dosa S, El-Tayeb A, Muller CE: Carbamazepine derivatives with P2X4 receptor-blocking activity. Bioorg Med Chem. 2014 Feb 1;22(3):1077-88. doi: 10.1016/j.bmc.2013.12.035. Epub 2013 Dec 25.
GroupsApproved
Direct ClassificationDibenzazepines
SMILESCC(=O)O[C@H]1CC2=CC=CC=C2N(C(N)=O)C2=CC=CC=C12
Pathways
PharmGKB
ChEMBLCHEMBL87992