| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS42000746 | EBV | ENSG00000145730.21 | protein_coding | PAM | No | No | 5066 | P19021 |
| TVIS10037201 | HBV | ENSG00000145730.21 | protein_coding | PAM | No | No | 5066 | P19021 |
| TVIS10020765 | HBV | ENSG00000145730.21 | protein_coding | PAM | No | No | 5066 | P19021 |
| TVIS30008827 | HIV | ENSG00000145730.21 | protein_coding | PAM | No | No | 5066 | P19021 |
| TVIS30008828 | HIV | ENSG00000145730.21 | protein_coding | PAM | No | No | 5066 | P19021 |
| TVIS30008829 | HIV | ENSG00000145730.21 | protein_coding | PAM | No | No | 5066 | P19021 |
| TVIS30080363 | HIV | ENSG00000145730.21 | protein_coding | PAM | No | No | 5066 | P19021 |
| TVIS30063101 | HIV | ENSG00000145730.21 | protein_coding | PAM | No | No | 5066 | P19021 |
| TVIS30063102 | HIV | ENSG00000145730.21 | protein_coding | PAM | No | No | 5066 | P19021 |
| TVIS30063103 | HIV | ENSG00000145730.21 | protein_coding | PAM | No | No | 5066 | P19021 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | PAM |
|---|---|
| DrugBank ID | DB00126 |
| Drug Name | Ascorbic acid |
| Target ID | BE0002200 |
| UniProt ID | P19021 |
| Regulation Type | cofactor |
| PubMed IDs | 17570561; 16773376; 17002377; 9211255 |
| Citations | Romero I, Teresa Sanchez-Ballesta M, Maldonado R, Isabel Escribano M, Merodio C: Anthocyanin, antioxidant activity and stress-induced gene expression in high CO2-treated table grapes stored at low temperature. J Plant Physiol. 2008;165(5):522-30. Epub 2007 Jun 13.@@Floryszak-Wieczorek J, Milczarek G, Arasimowicz M, Ciszewski A: Do nitric oxide donors mimic endogenous NO-related response in plants? Planta. 2006 Nov;224(6):1363-72. Epub 2006 Jun 14.@@Crespo A, Marti MA, Roitberg AE, Amzel LM, Estrin DA: The catalytic mechanism of peptidylglycine alpha-hydroxylating monooxygenase investigated by computer simulation. J Am Chem Soc. 2006 Oct 4;128(39):12817-28.@@Kolhekar AS, Mains RE, Eipper BA: Peptidylglycine alpha-amidating monooxygenase: an ascorbate-requiring enzyme. Methods Enzymol. 1997;279:35-43. doi: 10.1016/s0076-6879(97)79007-4. |
| Groups | Approved; Nutraceutical |
| Direct Classification | Butenolides |
| SMILES | [H][C@@]1(OC(=O)C(O)=C1O)[C@@H](O)CO |
| Pathways | Tyrosine Metabolism; Refsum Disease; The Oncogenic Action of Succinate; Disulfiram Action Pathway; Aromatic L-Aminoacid Decarboxylase Deficiency; Oxidation of Branched-Chain Fatty Acids; Catecholamine Biosynthesis; Monoamine Oxidase-A Deficiency (MAO-A); Tyrosinemia, Transient, of the Newborn; Carnitine Synthesis; Phytanic Acid Peroxisomal Oxidation; Hawkinsinuria; Dopamine beta-Hydroxylase Deficiency; Tyrosinemia Type I; Alkaptonuria; Tyrosine Hydroxylase Deficiency; The Oncogenic Action of Fumarate |
| PharmGKB | PA451898 |
| ChEMBL | CHEMBL196 |
