| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44012666 | HTLV-1 | ENSG00000123360.12 | protein_coding | PDE1B | No | No | 5153 | B4DK72 Q01064 |
| TVIS44020579 | HTLV-1 | ENSG00000123360.12 | protein_coding | PDE1B | No | No | 5153 | B4DK72 Q01064 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | PDE1B |
|---|---|
| DrugBank ID | DB00201 |
| Drug Name | Caffeine |
| Target ID | BE0009789 |
| UniProt ID | O76074 |
| Regulation Type | inhibitor |
| PubMed IDs | 16402111; 7689104 |
| Citations | Boswell-Smith V, Spina D, Page CP: Phosphodiesterase inhibitors. Br J Pharmacol. 2006 Jan;147 Suppl 1:S252-7. doi: 10.1038/sj.bjp.0706495.@@Howell LL: Comparative effects of caffeine and selective phosphodiesterase inhibitors on respiration and behavior in rhesus monkeys. J Pharmacol Exp Ther. 1993 Aug;266(2):894-903. |
| Groups | Approved |
| Direct Classification | Xanthines |
| SMILES | CN1C=NC2=C1C(=O)N(C)C(=O)N2C |
| Pathways | Caffeine Metabolism |
| PharmGKB | PA448710 |
| ChEMBL | CHEMBL113 |
