| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30007269 | HIV | ENSG00000185527.12 | protein_coding | PDE6G | No | No | 5148 | P18545 |
| TVIS30000178 | HIV | ENSG00000185527.12 | protein_coding | PDE6G | No | No | 5148 | P18545 |
| TVIS30017582 | HIV | ENSG00000185527.12 | protein_coding | PDE6G | No | No | 5148 | P18545 |
| TVIS20020716 | HPV | ENSG00000185527.12 | protein_coding | PDE6G | No | No | 5148 | P18545 |
| TVIS20020717 | HPV | ENSG00000185527.12 | protein_coding | PDE6G | No | No | 5148 | P18545 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | PDE6G |
|---|---|
| DrugBank ID | DB00203 |
| Drug Name | Sildenafil |
| Target ID | BE0003556 |
| UniProt ID | P18545 |
| Regulation Type | inhibitor |
| PubMed IDs | 16815627 |
| Citations | Uckert S, Hedlund P, Andersson KE, Truss MC, Jonas U, Stief CG: Update on phosphodiesterase (PDE) isoenzymes as pharmacologic targets in urology: present and future. Eur Urol. 2006 Dec;50(6):1194-207; discussion 1207. Epub 2006 Jun 6. |
| Groups | Approved; Investigational |
| Direct Classification | Benzenesulfonamides |
| SMILES | CCCC1=NN(C)C2=C1N=C(NC2=O)C1=CC(=CC=C1OCC)S(=O)(=O)N1CCN(C)CC1 |
| Pathways | |
| PharmGKB | PA451346 |
| ChEMBL | CHEMBL192 |
