| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10017304 | HBV | ENSG00000160209.19 | protein_coding | PDXK | No | No | 8566 | F2Z2Y4 O00764 |
| TVIS30054773 | HIV | ENSG00000160209.19 | protein_coding | PDXK | No | No | 8566 | F2Z2Y4 O00764 |
| TVIS20002225 | HPV | ENSG00000160209.19 | protein_coding | PDXK | No | No | 8566 | F2Z2Y4 O00764 |
| TVIS20068127 | HPV | ENSG00000160209.19 | protein_coding | PDXK | No | No | 8566 | F2Z2Y4 O00764 |
| TVIS20045247 | HPV | ENSG00000160209.19 | protein_coding | PDXK | No | No | 8566 | F2Z2Y4 O00764 |
| TVIS44042877 | HTLV-1 | ENSG00000160209.19 | protein_coding | PDXK | No | No | 8566 | F2Z2Y4 O00764 |
| TVIS44042961 | HTLV-1 | ENSG00000160209.19 | protein_coding | PDXK | No | No | 8566 | F2Z2Y4 O00764 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | PDXK |
|---|---|
| DrugBank ID | DB00147 |
| Drug Name | Pyridoxal |
| Target ID | BE0000042 |
| UniProt ID | O00764 |
| Regulation Type | |
| PubMed IDs | 15985434; 16494569; 16978644 |
| Citations | Tang L, Li MH, Cao P, Wang F, Chang WR, Bach S, Reinhardt J, Ferandin Y, Galons H, Wan Y, Gray N, Meijer L, Jiang T, Liang DC: Crystal structure of pyridoxal kinase in complex with roscovitine and derivatives. J Biol Chem. 2005 Sep 2;280(35):31220-9. Epub 2005 Jun 28.@@Adams JB, George F, Audhya T: Abnormally high plasma levels of vitamin B6 in children with autism not taking supplements compared to controls not taking supplements. J Altern Complement Med. 2006 Jan-Feb;12(1):59-63.@@Newman JA, Das SK, Sedelnikova SE, Rice DW: The crystal structure of an ADP complex of Bacillus subtilis pyridoxal kinase provides evidence for the parallel emergence of enzyme activity during evolution. J Mol Biol. 2006 Oct 20;363(2):520-30. Epub 2006 Aug 12. |
| Groups | Experimental; Nutraceutical |
| Direct Classification | Pyridoxals and derivatives |
| SMILES | CC1=NC=C(CO)C(C=O)=C1O |
| Pathways | 3-Methylglutaconic Aciduria Type III; 3-Methylglutaconic Aciduria Type I; beta-Ketothiolase Deficiency; Isovaleric Aciduria; Isobutyryl-CoA Dehydrogenase Deficiency; Propionic Acidemia; 3-Hydroxyisobutyric Aciduria; 3-Hydroxyisobutyric Acid Dehydrogenase Deficiency; Hypophosphatasia; Vitamin B6 Metabolism; 2-Methyl-3-hydroxybutryl-CoA Dehydrogenase Deficiency; 3-Methylcrotonyl-CoA Carboxylase Deficiency Type I; 3-Hydroxy-3-methylglutaryl-CoA Lyase Deficiency; Methylmalonic Aciduria; 3-Methylglutaconic Aciduria Type IV; Methylmalonate Semialdehyde Dehydrogenase Deficiency; Valine, Leucine, and Isoleucine Degradation; Maple Syrup Urine Disease; Isovaleric Acidemia |
| PharmGKB | PA164749166 |
| ChEMBL | CHEMBL102970 |
