| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10015071 | HBV | ENSG00000115896.17 | protein_coding | PLCL1 | No | No | 5334 | Q15111 |
| TVIS10015072 | HBV | ENSG00000115896.17 | protein_coding | PLCL1 | No | No | 5334 | Q15111 |
| TVIS10011818 | HBV | ENSG00000115896.17 | protein_coding | PLCL1 | No | No | 5334 | Q15111 |
| TVIS10003972 | HBV | ENSG00000115896.17 | protein_coding | PLCL1 | No | No | 5334 | Q15111 |
| TVIS10013894 | HBV | ENSG00000115896.17 | protein_coding | PLCL1 | No | No | 5334 | Q15111 |
| TVIS10012597 | HBV | ENSG00000115896.17 | protein_coding | PLCL1 | No | No | 5334 | Q15111 |
| TVIS10011028 | HBV | ENSG00000115896.17 | protein_coding | PLCL1 | No | No | 5334 | Q15111 |
| TVIS10012598 | HBV | ENSG00000115896.17 | protein_coding | PLCL1 | No | No | 5334 | Q15111 |
| TVIS10037148 | HBV | ENSG00000115896.17 | protein_coding | PLCL1 | No | No | 5334 | Q15111 |
| TVIS10028792 | HBV | ENSG00000115896.17 | protein_coding | PLCL1 | No | No | 5334 | Q15111 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | PLCL1 |
|---|---|
| DrugBank ID | DB01103 |
| Drug Name | Quinacrine |
| Target ID | BE0001081 |
| UniProt ID | Q15111 |
| Regulation Type | inhibitor |
| PubMed IDs | 11207202; 1860838; 2551803; 7573467; 8469910 |
| Citations | Biondi C, Pavan B, Ferretti ME, Corradini FG, Neri LM, Vesce F: Formyl-methionyl-leucyl-phenylalanine induces prostaglandin E2 release from human amnion-derived WISH cells by phospholipase C-mediated [Ca+]i rise. Biol Reprod. 2001 Mar;64(3):865-70.@@Takuwa N, Kumada M, Yamashita K, Takuwa Y: Mechanisms of bombesin-induced arachidonate mobilization in Swiss 3T3 fibroblasts. J Biol Chem. 1991 Aug 5;266(22):14237-43.@@Otamiri T: Phospholipase C-mediated intestinal mucosal damage is ameliorated by quinacrine. Food Chem Toxicol. 1989 Jun;27(6):399-402.@@Noveral JP, Grunstein MM: Tachykinin regulation of airway smooth muscle cell proliferation. Am J Physiol. 1995 Sep;269(3 Pt 1):L339-43.@@Bjoro T, Englund K, Torjesen PA, Haug E: Inhibitors of the arachidonic acid metabolism attenuate the thyroliberin (TRH) stimulated prolactin production without modifying the production of inositolphosphates in GH4C1 pituitary cells. Scand J Clin Lab Invest. 1993 Apr;53(2):111-6. |
| Groups | Investigational |
| Direct Classification | Acridines |
| SMILES | CCN(CC)CCCC(C)NC1=C2C=C(OC)C=CC2=NC2=C1C=CC(Cl)=C2 |
| Pathways | |
| PharmGKB | PA164745551 |
| ChEMBL | CHEMBL7568 |
