Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS30047445HIVENSG00000105355.9protein_codingPLIN3NoNo10226O60664
TVIS30047446HIVENSG00000105355.9protein_codingPLIN3NoNo10226O60664
TVIS30047447HIVENSG00000105355.9protein_codingPLIN3NoNo10226O60664
TVIS30047448HIVENSG00000105355.9protein_codingPLIN3NoNo10226O60664
TVIS30047449HIVENSG00000105355.9protein_codingPLIN3NoNo10226O60664
TVIS30047450HIVENSG00000105355.9protein_codingPLIN3NoNo10226O60664
TVIS30047451HIVENSG00000105355.9protein_codingPLIN3NoNo10226O60664
TVIS20067557HPVENSG00000105355.9protein_codingPLIN3NoNo10226O60664
TCGA Plot Options
Drug Information
GenePLIN3
DrugBank IDDB01271
Drug NameIdursulfase
Target IDBE0000856
UniProt IDO60664
Regulation Type
PubMed IDs17139284; 17016423; 18201153; 19707363; 18038146
CitationsOverington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Clarke LA: Idursulfase for the treatment of mucopolysaccharidosis II. Expert Opin Pharmacother. 2008 Feb;9(2):311-7. doi: 10.1517/14656566.9.2.311 .@@Burrow TA, Leslie ND: Review of the use of idursulfase in the treatment of mucopolysaccharidosis II. Biologics. 2008 Jun;2(2):311-20.@@Wraith JE, Scarpa M, Beck M, Bodamer OA, De Meirleir L, Guffon N, Meldgaard Lund A, Malm G, Van der Ploeg AT, Zeman J: Mucopolysaccharidosis type II (Hunter syndrome): a clinical review and recommendations for treatment in the era of enzyme replacement therapy. Eur J Pediatr. 2008 Mar;167(3):267-77. Epub 2007 Nov 23.
GroupsApproved
Direct ClassificationPeptides
SMILES
Pathways
PharmGKBPA164749134
ChEMBLCHEMBL1201826