| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10052955 | HBV | ENSG00000014138.10 | protein_coding | POLA2 | No | No | 23649 | Q14181 |
| TVIS30001880 | HIV | ENSG00000014138.10 | protein_coding | POLA2 | No | No | 23649 | Q14181 |
| TVIS30005828 | HIV | ENSG00000014138.10 | protein_coding | POLA2 | No | No | 23649 | Q14181 |
| TVIS30005829 | HIV | ENSG00000014138.10 | protein_coding | POLA2 | No | No | 23649 | Q14181 |
| TVIS30000100 | HIV | ENSG00000014138.10 | protein_coding | POLA2 | No | No | 23649 | Q14181 |
| TVIS30001022 | HIV | ENSG00000014138.10 | protein_coding | POLA2 | No | No | 23649 | Q14181 |
| TVIS30004409 | HIV | ENSG00000014138.10 | protein_coding | POLA2 | No | No | 23649 | Q14181 |
| TVIS30075388 | HIV | ENSG00000014138.10 | protein_coding | POLA2 | No | No | 23649 | Q14181 |
| TVIS30029989 | HIV | ENSG00000014138.10 | protein_coding | POLA2 | No | No | 23649 | Q14181 |
| TVIS30029990 | HIV | ENSG00000014138.10 | protein_coding | POLA2 | No | No | 23649 | Q14181 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | POLA2 |
|---|---|
| DrugBank ID | DB00851 |
| Drug Name | Dacarbazine |
| Target ID | BE0000716 |
| UniProt ID | Q14181 |
| Regulation Type | other/unknown |
| PubMed IDs | 17139284; 17016423; 3098406 |
| Citations | Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Lonn U, Lohn S: Prevention of dacarbazine damage of human neoplastic cell DNA by aphidicolin. Cancer Res. 1987 Jan 1;47(1):26-30. |
| Groups | Approved; Investigational |
| Direct Classification | 2-heteroaryl carboxamides |
| SMILES | CN(C)N=NC1=C(N=CN1)C(N)=O |
| Pathways | |
| PharmGKB | PA449197 |
| ChEMBL | CHEMBL476 |
