Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS30011012HIVENSG00000005249.14protein_codingPRKAR2BNoNo5577P31323
TVIS30078023HIVENSG00000005249.14protein_codingPRKAR2BNoNo5577P31323
TVIS20061591HPVENSG00000005249.14protein_codingPRKAR2BNoNo5577P31323
TVIS44033790HTLV-1ENSG00000005249.14protein_codingPRKAR2BNoNo5577P31323
TCGA Plot Options
Drug Information
GenePRKAR2B
DrugBank IDDB02527
Drug NameCyclic adenosine monophosphate
Target IDBE0004497
UniProt IDP31323
Regulation Type
PubMed IDs17139284; 17016423; 10592235
CitationsOverington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.
GroupsExperimental
Direct Classification3',5'-cyclic purine nucleotides
SMILESNC1=C2N=CN([C@@H]3O[C@@H]4COP(O)(=O)O[C@H]4[C@H]3O)C2=NC=N1
PathwaysMolybdenum Cofactor Deficiency; Excitatory Neural Signalling Through 5-HTR 6 and Serotonin; Intracellular Signalling Through FSH Receptor and Follicle Stimulating Hormone; Xanthinuria Type I; Azathioprine Action Pathway; AICA-Ribosiduria; Lysophosphatidic Acid LPA5 Signalling; Excitatory Neural Signalling Through 5-HTR 7 and Serotonin; Purine Nucleoside Phosphorylase Deficiency; Lysophosphatidic Acid LPA6 Signalling; Excitatory Neural Signalling Through 5-HTR 4 and Serotonin; Vasopressin Regulation of Water Homeostasis; Corticotropin Activation of Cortisol Production; Thioguanine Action Pathway; Intracellular Signalling Through Histamine H2 Receptor and Histamine; Xanthine Dehydrogenase Deficiency (Xanthinuria); Intracellular Signalling Through PGD2 receptor and Prostaglandin D2; Intracellular Signalling Through Adenosine Receptor A2b and Adenosine; Purine Metabolism; Intracellular Signalling Through Adenosine Receptor A2a and Adenosine; Lysophosphatidic Acid LPA1 Signalling; Mitochondrial DNA Depletion Syndrome; Adenosine Deaminase Deficiency; Lysophosphatidic Acid LPA4 Signalling; Xanthinuria Type II; Myoadenylate Deaminase Deficiency; Lysophosphatidic Acid LPA2 Signalling; Intracellular Signalling Through Prostacyclin Receptor and Prostacyclin; Dopamine Activation of Neurological Reward System; Adenylosuccinate Lyase Deficiency
PharmGKB
ChEMBLCHEMBL316966