| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS46001155 | BKPyv | ENSG00000113494.17 | protein_coding | PRLR | No | No | 5618 | P16471 |
| TVIS46001329 | BKPyv | ENSG00000113494.17 | protein_coding | PRLR | No | No | 5618 | P16471 |
| TVIS10037908 | HBV | ENSG00000113494.17 | protein_coding | PRLR | No | No | 5618 | P16471 |
| TVIS10049313 | HBV | ENSG00000113494.17 | protein_coding | PRLR | No | No | 5618 | P16471 |
| TVIS30079578 | HIV | ENSG00000113494.17 | protein_coding | PRLR | No | No | 5618 | P16471 |
| TVIS30082569 | HIV | ENSG00000113494.17 | protein_coding | PRLR | No | No | 5618 | P16471 |
| TVIS30062107 | HIV | ENSG00000113494.17 | protein_coding | PRLR | No | No | 5618 | P16471 |
| TVIS30062108 | HIV | ENSG00000113494.17 | protein_coding | PRLR | No | No | 5618 | P16471 |
| TVIS20059269 | HPV | ENSG00000113494.17 | protein_coding | PRLR | No | No | 5618 | P16471 |
| TVIS20030367 | HPV | ENSG00000113494.17 | protein_coding | PRLR | No | No | 5618 | P16471 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | PRLR |
|---|---|
| DrugBank ID | DB00052 |
| Drug Name | Somatotropin |
| Target ID | BE0000345 |
| UniProt ID | P16471 |
| Regulation Type | ligand |
| PubMed IDs | 17279774; 17395896; 17317019; 2270485 |
| Citations | Keeler C, Jablonski EM, Albert YB, Taylor BD, Myszka DG, Clevenger CV, Hodsdon ME: The kinetics of binding human prolactin, but not growth hormone, to the prolactin receptor vary over a physiologic pH range. Biochemistry. 2007 Mar 6;46(9):2398-410. Epub 2007 Feb 6.@@Ahmed TA, Buzzelli MD, Lang CH, Capen JB, Shumate ML, Navaratnarajah M, Nagarajan M, Cooney RN: Interleukin-6 inhibits growth hormone-mediated gene expression in hepatocytes. Am J Physiol Gastrointest Liver Physiol. 2007 Jun;292(6):G1793-803. Epub 2007 Mar 29.@@Moderscheim TA, Gorba T, Pathipati P, Kokay IC, Grattan DR, Williams CE, Scheepens A: Prolactin is involved in glial responses following a focal injury to the juvenile rat brain. Neuroscience. 2007 Mar 30;145(3):963-73. Epub 2007 Feb 20.@@Cunningham BC, Bass S, Fuh G, Wells JA: Zinc mediation of the binding of human growth hormone to the human prolactin receptor. Science. 1990 Dec 21;250(4988):1709-12. |
| Groups | Approved; Investigational |
| Direct Classification | Peptides |
| SMILES | |
| Pathways | |
| PharmGKB | PA451446 |
| ChEMBL | CHEMBL1201621 |
