| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30006424 | HIV | ENSG00000100804.19 | protein_coding | PSMB5 | No | No | 5693 | P28074 |
| TVIS30011873 | HIV | ENSG00000100804.19 | protein_coding | PSMB5 | No | No | 5693 | P28074 |
| TVIS20008840 | HPV | ENSG00000100804.19 | protein_coding | PSMB5 | No | No | 5693 | P28074 |
| TVIS44051063 | HTLV-1 | ENSG00000100804.19 | protein_coding | PSMB5 | No | No | 5693 | P28074 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | PSMB5 |
|---|---|
| DrugBank ID | DB00188 |
| Drug Name | Bortezomib |
| Target ID | BE0002348 |
| UniProt ID | P28074 |
| Regulation Type | inhibitor |
| PubMed IDs | 15846363; 21247388 |
| Citations | Berkers CR, Verdoes M, Lichtman E, Fiebiger E, Kessler BM, Anderson KC, Ploegh HL, Ovaa H, Galardy PJ: Activity probe for in vivo profiling of the specificity of proteasome inhibitor bortezomib. Nat Methods. 2005 May;2(5):357-62. Epub 2005 Apr 21.@@Chen D, Frezza M, Schmitt S, Kanwar J, Dou QP: Bortezomib as the first proteasome inhibitor anticancer drug: current status and future perspectives. Curr Cancer Drug Targets. 2011 Mar;11(3):239-53. doi: 10.2174/156800911794519752. |
| Groups | Approved; Investigational |
| Direct Classification | Phenylalanine and derivatives |
| SMILES | CC(C)C[C@H](NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)C1=CN=CC=N1)B(O)O |
| Pathways | |
| PharmGKB | PA10252 |
| ChEMBL | CHEMBL325041 |
