Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS30003844HIVENSG00000240065.9protein_codingPSMB9NoNo5698P28065
TVIS30009028HIVENSG00000240065.9protein_codingPSMB9NoNo5698P28065
TVIS30009029HIVENSG00000240065.9protein_codingPSMB9NoNo5698P28065
TVIS30004920HIVENSG00000240065.9protein_codingPSMB9NoNo5698P28065
TVIS30016395HIVENSG00000240065.9protein_codingPSMB9NoNo5698P28065
TVIS30074686HIVENSG00000240065.9protein_codingPSMB9NoNo5698P28065
TVIS30019150HIVENSG00000240065.9protein_codingPSMB9NoNo5698P28065
TVIS30020803HIVENSG00000240065.9protein_codingPSMB9NoNo5698P28065
TVIS44012811HTLV-1ENSG00000240065.9protein_codingPSMB9NoNo5698P28065
TCGA Plot Options
Drug Information
GenePSMB9
DrugBank IDDB08889
Drug NameCarfilzomib
Target IDBE0004737
UniProt IDP28065
Regulation Typeinhibitor
PubMed IDs17591945
CitationsKuhn DJ, Chen Q, Voorhees PM, Strader JS, Shenk KD, Sun CM, Demo SD, Bennett MK, van Leeuwen FW, Chanan-Khan AA, Orlowski RZ: Potent activity of carfilzomib, a novel, irreversible inhibitor of the ubiquitin-proteasome pathway, against preclinical models of multiple myeloma. Blood. 2007 Nov 1;110(9):3281-90. Epub 2007 Jun 25.
GroupsApproved; Investigational
Direct ClassificationOligopeptides
SMILESCC(C)C[C@H](NC(=O)[C@H](CCC1=CC=CC=C1)NC(=O)CN1CCOCC1)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(C)C)C(=O)[C@@]1(C)CO1
Pathways
PharmGKBPA166165203
ChEMBLCHEMBL451887