| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44046795 | HTLV-1 | ENSG00000111679.17 | protein_coding | PTPN6 | No | No | 5777 | P29350 Q53XS4 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | PTPN6 |
|---|---|
| DrugBank ID | DB01133 |
| Drug Name | Tiludronic acid |
| Target ID | BE0009941 |
| UniProt ID | P29350 |
| Regulation Type | inhibitor |
| PubMed IDs | 9145236; 19189046 |
| Citations | Murakami H, Takahashi N, Tanaka S, Nakamura I, Udagawa N, Nakajo S, Nakaya K, Abe M, Yuda Y, Konno F, Barbier A, Suda T: Tiludronate inhibits protein tyrosine phosphatase activity in osteoclasts. Bone. 1997 May;20(5):399-404.@@Sheng MH, Lau KH: Role of protein-tyrosine phosphatases in regulation of osteoclastic activity. Cell Mol Life Sci. 2009 Jun;66(11-12):1946-61. doi: 10.1007/s00018-009-8811-5. |
| Groups | Approved; Investigational; Vet_approved |
| Direct Classification | Bisphosphonates |
| SMILES | OP(O)(=O)C(SC1=CC=C(Cl)C=C1)P(O)(O)=O |
| Pathways | |
| PharmGKB | PA451688 |
| ChEMBL | CHEMBL1350 |
