| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS42001025 | EBV | ENSG00000105426.19 | protein_coding | PTPRS | No | Yes | 5802 | Q13332 Q8NHS7 |
| TVIS30079008 | HIV | ENSG00000105426.19 | protein_coding | PTPRS | No | Yes | 5802 | Q13332 Q8NHS7 |
| TVIS30080044 | HIV | ENSG00000105426.19 | protein_coding | PTPRS | No | Yes | 5802 | Q13332 Q8NHS7 |
| TVIS30079133 | HIV | ENSG00000105426.19 | protein_coding | PTPRS | No | Yes | 5802 | Q13332 Q8NHS7 |
| TVIS30047483 | HIV | ENSG00000105426.19 | protein_coding | PTPRS | No | Yes | 5802 | Q13332 Q8NHS7 |
| TVIS20009586 | HPV | ENSG00000105426.19 | protein_coding | PTPRS | No | Yes | 5802 | Q13332 Q8NHS7 |
| TVIS20054067 | HPV | ENSG00000105426.19 | protein_coding | PTPRS | No | Yes | 5802 | Q13332 Q8NHS7 |
| TVIS20025046 | HPV | ENSG00000105426.19 | protein_coding | PTPRS | No | Yes | 5802 | Q13332 Q8NHS7 |
| TVIS20039856 | HPV | ENSG00000105426.19 | protein_coding | PTPRS | No | Yes | 5802 | Q13332 Q8NHS7 |
| TVIS44047902 | HTLV-1 | ENSG00000105426.19 | protein_coding | PTPRS | No | Yes | 5802 | Q13332 Q8NHS7 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | PTPRS |
|---|---|
| DrugBank ID | DB00630 |
| Drug Name | Alendronic acid |
| Target ID | BE0003567 |
| UniProt ID | Q13332 |
| Regulation Type | inhibitor |
| PubMed IDs | 9310349; 8610169; 11752352 |
| Citations | Opas EE, Rutledge SJ, Golub E, Stern A, Zimolo Z, Rodan GA, Schmidt A: Alendronate inhibition of protein-tyrosine-phosphatase-meg1. Biochem Pharmacol. 1997 Sep 15;54(6):721-7.@@Schmidt A, Rutledge SJ, Endo N, Opas EE, Tanaka H, Wesolowski G, Leu CT, Huang Z, Ramachandaran C, Rodan SB, Rodan GA: Protein-tyrosine phosphatase activity regulates osteoclast formation and function: inhibition by alendronate. Proc Natl Acad Sci U S A. 1996 Apr 2;93(7):3068-73.@@Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. |
| Groups | Approved |
| Direct Classification | Bisphosphonates |
| SMILES | NCCCC(O)(P(O)(O)=O)P(O)(O)=O |
| Pathways | Alendronate Action Pathway |
| PharmGKB | PA448082 |
| ChEMBL | CHEMBL870 |
