| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30010984 | HIV | ENSG00000136238.20 | protein_coding | RAC1 | Yes | No | 5879 | A4D2P0 A4D2P1 P63000 |
| TVIS30009240 | HIV | ENSG00000136238.20 | protein_coding | RAC1 | Yes | No | 5879 | A4D2P0 A4D2P1 P63000 |
| TVIS30066391 | HIV | ENSG00000136238.20 | protein_coding | RAC1 | Yes | No | 5879 | A4D2P0 A4D2P1 P63000 |
| TVIS30066392 | HIV | ENSG00000136238.20 | protein_coding | RAC1 | Yes | No | 5879 | A4D2P0 A4D2P1 P63000 |
| TVIS30066393 | HIV | ENSG00000136238.20 | protein_coding | RAC1 | Yes | No | 5879 | A4D2P0 A4D2P1 P63000 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | RAC1 |
|---|---|
| DrugBank ID | DB00993 |
| Drug Name | Azathioprine |
| Target ID | BE0001109 |
| UniProt ID | P63000 |
| Regulation Type | modulator |
| PubMed IDs | 12697733 |
| Citations | Tiede I, Fritz G, Strand S, Poppe D, Dvorsky R, Strand D, Lehr HA, Wirtz S, Becker C, Atreya R, Mudter J, Hildner K, Bartsch B, Holtmann M, Blumberg R, Walczak H, Iven H, Galle PR, Ahmadian MR, Neurath MF: CD28-dependent Rac1 activation is the molecular target of azathioprine in primary human CD4+ T lymphocytes. J Clin Invest. 2003 Apr;111(8):1133-45. |
| Groups | Approved |
| Direct Classification | Diarylthioethers |
| SMILES | CN1C=NC(=C1SC1=NC=NC2=C1NC=N2)[N+]([O-])=O |
| Pathways | Azathioprine Action Pathway; Azathioprine Metabolism Pathway |
| PharmGKB | PA448515 |
| ChEMBL | CHEMBL1542 |
