Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS30080333HIVENSG00000118849.10protein_codingRARRES1NoNo5918P49788
TVIS20022955HPVENSG00000118849.10protein_codingRARRES1NoNo5918P49788
TCGA Plot Options
Drug Information
GeneRARRES1
DrugBank IDDB00755
Drug NameTretinoin
Target IDBE0000653
UniProt IDP49788
Regulation Typeagonist
PubMed IDs15059893; 15897880
CitationsYoussef EM, Chen XQ, Higuchi E, Kondo Y, Garcia-Manero G, Lotan R, Issa JP: Hypermethylation and silencing of the putative tumor suppressor Tazarotene-induced gene 1 in human cancers. Cancer Res. 2004 Apr 1;64(7):2411-7.@@Zirn B, Samans B, Spangenberg C, Graf N, Eilers M, Gessler M: All-trans retinoic acid treatment of Wilms tumor cells reverses expression of genes associated with high risk and relapse in vivo. Oncogene. 2005 Aug 4;24(33):5246-51.
GroupsApproved; Investigational; Nutraceutical
Direct Classification
SMILESCC(C=CC1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C/C(O)=O
PathwaysRetinol Metabolism; Vitamin A Deficiency
PharmGKBPA164746900
ChEMBLCHEMBL38