| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10005679 | HBV | ENSG00000116745.8 | protein_coding | RPE65 | No | No | 6121 | Q16518 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | RPE65 |
|---|---|
| DrugBank ID | DB13932 |
| Drug Name | Voretigene neparvovec |
| Target ID | BE0009149 |
| UniProt ID | Q16518 |
| Regulation Type | gene replacement |
| PubMed IDs | 19649989; 18441370 |
| Citations | Deyle DR, Russell DW: Adeno-associated virus vector integration. Curr Opin Mol Ther. 2009 Aug;11(4):442-7.@@Maguire AM, Simonelli F, Pierce EA, Pugh EN Jr, Mingozzi F, Bennicelli J, Banfi S, Marshall KA, Testa F, Surace EM, Rossi S, Lyubarsky A, Arruda VR, Konkle B, Stone E, Sun J, Jacobs J, Dell'Osso L, Hertle R, Ma JX, Redmond TM, Zhu X, Hauck B, Zelenaia O, Shindler KS, Maguire MG, Wright JF, Volpe NJ, McDonnell JW, Auricchio A, High KA, Bennett J: Safety and efficacy of gene transfer for Leber's congenital amaurosis. N Engl J Med. 2008 May 22;358(21):2240-8. doi: 10.1056/NEJMoa0802315. Epub 2008 Apr 27. |
| Groups | Approved |
| Direct Classification | |
| SMILES | |
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| ChEMBL |
