| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30078084 | HIV | ENSG00000196154.12 | protein_coding | S100A4 | No | No | 6275 | P26447 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | S100A4 |
|---|---|
| DrugBank ID | DB00831 |
| Drug Name | Trifluoperazine |
| Target ID | BE0004350 |
| UniProt ID | P26447 |
| Regulation Type | inhibitor |
| PubMed IDs | 10592235; 20421509 |
| Citations | Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.@@Malashkevich VN, Dulyaninova NG, Ramagopal UA, Liriano MA, Varney KM, Knight D, Brenowitz M, Weber DJ, Almo SC, Bresnick AR: Phenothiazines inhibit S100A4 function by inducing protein oligomerization. Proc Natl Acad Sci U S A. 2010 May 11;107(19):8605-10. doi: 10.1073/pnas.0913660107. Epub 2010 Apr 26. |
| Groups | Approved; Investigational |
| Direct Classification | Phenothiazines |
| SMILES | CN1CCN(CCCN2C3=CC=CC=C3SC3=C2C=C(C=C3)C(F)(F)F)CC1 |
| Pathways | |
| PharmGKB | PA451771 |
| ChEMBL | CHEMBL422 |
