Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10008849HBVENSG00000153253.20protein_codingSCN3ANoNo6328Q9C007
Q9NY46
TVIS10045247HBVENSG00000153253.20protein_codingSCN3ANoNo6328Q9C007
Q9NY46
TVIS10045248HBVENSG00000153253.20protein_codingSCN3ANoNo6328Q9C007
Q9NY46
TVIS30078418HIVENSG00000153253.20protein_codingSCN3ANoNo6328Q9C007
Q9NY46
TVIS30051607HIVENSG00000153253.20protein_codingSCN3ANoNo6328Q9C007
Q9NY46
TVIS30051608HIVENSG00000153253.20protein_codingSCN3ANoNo6328Q9C007
Q9NY46
TVIS30051609HIVENSG00000153253.20protein_codingSCN3ANoNo6328Q9C007
Q9NY46
TVIS20014944HPVENSG00000153253.20protein_codingSCN3ANoNo6328Q9C007
Q9NY46
TVIS20042156HPVENSG00000153253.20protein_codingSCN3ANoNo6328Q9C007
Q9NY46
TVIS20016130HPVENSG00000153253.20protein_codingSCN3ANoNo6328Q9C007
Q9NY46
TCGA Plot Options
Drug Information
GeneSCN3A
DrugBank IDDB00252
Drug NamePhenytoin
Target IDBE0002082
UniProt IDQ9NY46
Regulation Type
PubMed IDs15922564; 15805193
CitationsLucas PT, Meadows LS, Nicholls J, Ragsdale DS: An epilepsy mutation in the beta1 subunit of the voltage-gated sodium channel results in reduced channel sensitivity to phenytoin. Epilepsy Res. 2005 May;64(3):77-84.@@Tate SK, Depondt C, Sisodiya SM, Cavalleri GL, Schorge S, Soranzo N, Thom M, Sen A, Shorvon SD, Sander JW, Wood NW, Goldstein DB: Genetic predictors of the maximum doses patients receive during clinical use of the anti-epileptic drugs carbamazepine and phenytoin. Proc Natl Acad Sci U S A. 2005 Apr 12;102(15):5507-12. Epub 2005 Apr 1.
GroupsApproved; Vet_approved
Direct ClassificationPhenylhydantoins
SMILESO=C1NC(=O)C(N1)(C1=CC=CC=C1)C1=CC=CC=C1
PathwaysFosphenytoin (Antiarrhythmic) Action Pathway; Fosphenytoin (Antiarrhythmic) Metabolism Pathway; Phenytoin (Antiarrhythmic) Action Pathway
PharmGKBPA450947
ChEMBLCHEMBL16