| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10009167 | HBV | ENSG00000183873.20 | protein_coding | SCN5A | No | No | 6331 | E9PG18 E9PHB6 H9KVD2 K4DIA1 Q14524 Q86V90 |
| TVIS20012030 | HPV | ENSG00000183873.20 | protein_coding | SCN5A | No | No | 6331 | E9PG18 E9PHB6 H9KVD2 K4DIA1 Q14524 Q86V90 |
| TVIS20036049 | HPV | ENSG00000183873.20 | protein_coding | SCN5A | No | No | 6331 | E9PG18 E9PHB6 H9KVD2 K4DIA1 Q14524 Q86V90 |
| TVIS20056806 | HPV | ENSG00000183873.20 | protein_coding | SCN5A | No | No | 6331 | E9PG18 E9PHB6 H9KVD2 K4DIA1 Q14524 Q86V90 |
| TVIS44025067 | HTLV-1 | ENSG00000183873.20 | protein_coding | SCN5A | No | No | 6331 | E9PG18 E9PHB6 H9KVD2 K4DIA1 Q14524 Q86V90 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | SCN5A |
|---|---|
| DrugBank ID | DB00192 |
| Drug Name | Indecainide |
| Target ID | BE0000197 |
| UniProt ID | Q14524 |
| Regulation Type | inhibitor |
| PubMed IDs | 17139284; 17016423; 11752352; 2688391; 2476626; 6206315 |
| Citations | Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5.@@Jaillon P, Drici M: Recent antiarrhythmic drugs. Am J Cardiol. 1989 Dec 5;64(20):65J-69J.@@Holland DR, Lacefield WB, Gonzales CR, Johnston SR, Turk JA: Indecainide: effects on arrhythmias, electrophysiology, and cardiovascular dynamics. J Cardiovasc Pharmacol. 1989 Sep;14(3):454-61.@@Steinberg MI, Wiest SA: Electrophysiological studies of indecainide hydrochloride, a new antiarrhythmic agent, in canine cardiac tissues. J Cardiovasc Pharmacol. 1984 Jul-Aug;6(4):614-21. |
| Groups | Approved |
| Direct Classification | Fluorenes |
| SMILES | CC(C)NCCCC1(C(N)=O)C2=CC=CC=C2C2=CC=CC=C12 |
| Pathways | |
| PharmGKB | PA164754881 |
| ChEMBL | CHEMBL1201242 |
