| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10035581 | HBV | ENSG00000196876.19 | protein_coding | SCN8A | No | No | 6334 | Q6B4S4 Q9UQD0 |
| TVIS10041398 | HBV | ENSG00000196876.19 | protein_coding | SCN8A | No | No | 6334 | Q6B4S4 Q9UQD0 |
| TVIS30076959 | HIV | ENSG00000196876.19 | protein_coding | SCN8A | No | No | 6334 | Q6B4S4 Q9UQD0 |
| TVIS30032911 | HIV | ENSG00000196876.19 | protein_coding | SCN8A | No | No | 6334 | Q6B4S4 Q9UQD0 |
| TVIS30032912 | HIV | ENSG00000196876.19 | protein_coding | SCN8A | No | No | 6334 | Q6B4S4 Q9UQD0 |
| TVIS30032913 | HIV | ENSG00000196876.19 | protein_coding | SCN8A | No | No | 6334 | Q6B4S4 Q9UQD0 |
| TVIS30032914 | HIV | ENSG00000196876.19 | protein_coding | SCN8A | No | No | 6334 | Q6B4S4 Q9UQD0 |
| TVIS30032915 | HIV | ENSG00000196876.19 | protein_coding | SCN8A | No | No | 6334 | Q6B4S4 Q9UQD0 |
| TVIS30032916 | HIV | ENSG00000196876.19 | protein_coding | SCN8A | No | No | 6334 | Q6B4S4 Q9UQD0 |
| TVIS30032917 | HIV | ENSG00000196876.19 | protein_coding | SCN8A | No | No | 6334 | Q6B4S4 Q9UQD0 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | SCN8A |
|---|---|
| DrugBank ID | DB00252 |
| Drug Name | Phenytoin |
| Target ID | BE0002084 |
| UniProt ID | Q9UQD0 |
| Regulation Type | inhibitor |
| PubMed IDs | 15805193 |
| Citations | Tate SK, Depondt C, Sisodiya SM, Cavalleri GL, Schorge S, Soranzo N, Thom M, Sen A, Shorvon SD, Sander JW, Wood NW, Goldstein DB: Genetic predictors of the maximum doses patients receive during clinical use of the anti-epileptic drugs carbamazepine and phenytoin. Proc Natl Acad Sci U S A. 2005 Apr 12;102(15):5507-12. Epub 2005 Apr 1. |
| Groups | Approved; Vet_approved |
| Direct Classification | Phenylhydantoins |
| SMILES | O=C1NC(=O)C(N1)(C1=CC=CC=C1)C1=CC=CC=C1 |
| Pathways | Fosphenytoin (Antiarrhythmic) Action Pathway; Fosphenytoin (Antiarrhythmic) Metabolism Pathway; Phenytoin (Antiarrhythmic) Action Pathway |
| PharmGKB | PA450947 |
| ChEMBL | CHEMBL16 |
