| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10037580 | HBV | ENSG00000168447.11 | protein_coding | SCNN1B | No | No | 6338 | B2R812 P51168 |
| TVIS30040586 | HIV | ENSG00000168447.11 | protein_coding | SCNN1B | No | No | 6338 | B2R812 P51168 |
| TVIS20043413 | HPV | ENSG00000168447.11 | protein_coding | SCNN1B | No | No | 6338 | B2R812 P51168 |
| TVIS20041991 | HPV | ENSG00000168447.11 | protein_coding | SCNN1B | No | No | 6338 | B2R812 P51168 |
| TVIS20020651 | HPV | ENSG00000168447.11 | protein_coding | SCNN1B | No | No | 6338 | B2R812 P51168 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | SCNN1B |
|---|---|
| DrugBank ID | DB00384 |
| Drug Name | Triamterene |
| Target ID | BE0000024 |
| UniProt ID | P51168 |
| Regulation Type | inhibitor |
| PubMed IDs | 17139284; 17016423; 8772124; 11509829 |
| Citations | Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.@@Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34.@@Busch AE, Suessbrich H, Kunzelmann K, Hipper A, Greger R, Waldegger S, Mutschler E, Lindemann B, Lang F: Blockade of epithelial Na+ channels by triamterenes - underlying mechanisms and molecular basis. Pflugers Arch. 1996 Sep;432(5):760-6.@@Wagner CA, Ott M, Klingel K, Beck S, Melzig J, Friedrich B, Wild KN, Broer S, Moschen I, Albers A, Waldegger S, Tummler B, Egan ME, Geibel JP, Kandolf R, Lang F: Effects of the serine/threonine kinase SGK1 on the epithelial Na(+) channel (ENaC) and CFTR: implications for cystic fibrosis. Cell Physiol Biochem. 2001;11(4):209-18. |
| Groups | Approved |
| Direct Classification | Pteridines and derivatives |
| SMILES | NC1=NC(N)=C2N=C(C(N)=NC2=N1)C1=CC=CC=C1 |
| Pathways | Triamterene Action Pathway |
| PharmGKB | PA451752 |
| ChEMBL | CHEMBL585 |
