| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10000711 | HBV | ENSG00000111252.11 | protein_coding | SH2B3 | No | Yes | 10019 | F5GYM4 Q96BA5 Q9UQQ2 |
| TVIS10000712 | HBV | ENSG00000111252.11 | protein_coding | SH2B3 | No | Yes | 10019 | F5GYM4 Q96BA5 Q9UQQ2 |
| TVIS10024642 | HBV | ENSG00000111252.11 | protein_coding | SH2B3 | No | Yes | 10019 | F5GYM4 Q96BA5 Q9UQQ2 |
| TVIS10026971 | HBV | ENSG00000111252.11 | protein_coding | SH2B3 | No | Yes | 10019 | F5GYM4 Q96BA5 Q9UQQ2 |
| TVIS10024643 | HBV | ENSG00000111252.11 | protein_coding | SH2B3 | No | Yes | 10019 | F5GYM4 Q96BA5 Q9UQQ2 |
| TVIS10026972 | HBV | ENSG00000111252.11 | protein_coding | SH2B3 | No | Yes | 10019 | F5GYM4 Q96BA5 Q9UQQ2 |
| TVIS10050486 | HBV | ENSG00000111252.11 | protein_coding | SH2B3 | No | Yes | 10019 | F5GYM4 Q96BA5 Q9UQQ2 |
| TVIS30014986 | HIV | ENSG00000111252.11 | protein_coding | SH2B3 | No | Yes | 10019 | F5GYM4 Q96BA5 Q9UQQ2 |
| TVIS30087547 | HIV | ENSG00000111252.11 | protein_coding | SH2B3 | No | Yes | 10019 | F5GYM4 Q96BA5 Q9UQQ2 |
| TVIS20012496 | HPV | ENSG00000111252.11 | protein_coding | SH2B3 | No | Yes | 10019 | F5GYM4 Q96BA5 Q9UQQ2 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | SH2B3 |
|---|---|
| DrugBank ID | DB06589 |
| Drug Name | Pazopanib |
| Target ID | BE0004714 |
| UniProt ID | Q9UQQ2 |
| Regulation Type | inhibitor |
| PubMed IDs | 23072642 |
| Citations | Deeks ED: Pazopanib: in advanced soft tissue sarcoma. Drugs. 2012 Nov 12;72(16):2129-40. doi: 10.2165/11209950-000000000-00000. |
| Groups | Approved |
| Direct Classification | Alkyldiarylamines |
| SMILES | CN(C1=CC2=NN(C)C(C)=C2C=C1)C1=CC=NC(NC2=CC=C(C)C(=C2)S(N)(=O)=O)=N1 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL477772 |
