| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10048879 | HBV | ENSG00000118596.12 | protein_coding | SLC16A7 | No | No | 9194 | O60669 |
| TVIS30033387 | HIV | ENSG00000118596.12 | protein_coding | SLC16A7 | No | No | 9194 | O60669 |
| TVIS30033388 | HIV | ENSG00000118596.12 | protein_coding | SLC16A7 | No | No | 9194 | O60669 |
| TVIS30033389 | HIV | ENSG00000118596.12 | protein_coding | SLC16A7 | No | No | 9194 | O60669 |
| TVIS30033390 | HIV | ENSG00000118596.12 | protein_coding | SLC16A7 | No | No | 9194 | O60669 |
| TVIS30033391 | HIV | ENSG00000118596.12 | protein_coding | SLC16A7 | No | No | 9194 | O60669 |
| TVIS30033392 | HIV | ENSG00000118596.12 | protein_coding | SLC16A7 | No | No | 9194 | O60669 |
| TVIS30033393 | HIV | ENSG00000118596.12 | protein_coding | SLC16A7 | No | No | 9194 | O60669 |
| TVIS30033394 | HIV | ENSG00000118596.12 | protein_coding | SLC16A7 | No | No | 9194 | O60669 |
| TVIS30033395 | HIV | ENSG00000118596.12 | protein_coding | SLC16A7 | No | No | 9194 | O60669 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | SLC16A7 |
|---|---|
| DrugBank ID | DB00119 |
| Drug Name | Pyruvic acid |
| Target ID | BE0000440 |
| UniProt ID | O60669 |
| Regulation Type | |
| PubMed IDs | 16604139; 16766717; 17556391; 16597615; 15953344 |
| Citations | Bonen A, Heynen M, Hatta H: Distribution of monocarboxylate transporters MCT1-MCT8 in rat tissues and human skeletal muscle. Appl Physiol Nutr Metab. 2006 Feb;31(1):31-9.@@Hinoi E, Takarada T, Tsuchihashi Y, Fujimori S, Moriguchi N, Wang L, Uno K, Yoneda Y: A molecular mechanism of pyruvate protection against cytotoxicity of reactive oxygen species in osteoblasts. Mol Pharmacol. 2006 Sep;70(3):925-35. Epub 2006 Jun 9.@@Yoshida Y, Holloway GP, Ljubicic V, Hatta H, Spriet LL, Hood DA, Bonen A: Negligible direct lactate oxidation in subsarcolemmal and intermyofibrillar mitochondria obtained from red and white rat skeletal muscle. J Physiol. 2007 Aug 1;582(Pt 3):1317-35. Epub 2007 Jun 7.@@de Laplanche E, Gouget K, Cleris G, Dragounoff F, Demont J, Morales A, Bezin L, Godinot C, Perriere G, Mouchiroud D, Simonnet H: Physiological oxygenation status is required for fully differentiated phenotype in kidney cortex proximal tubules. Am J Physiol Renal Physiol. 2006 Oct;291(4):F750-60. Epub 2006 Apr 4.@@Pierre K, Pellerin L: Monocarboxylate transporters in the central nervous system: distribution, regulation and function. J Neurochem. 2005 Jul;94(1):1-14. |
| Groups | Approved; Investigational; Nutraceutical |
| Direct Classification | Alpha-keto acids and derivatives |
| SMILES | CC(=O)C(O)=O |
| Pathways | Citrullinemia Type I; 4-Hydroxybutyric Aciduria/Succinic Semialdehyde Dehydrogenase Deficiency; Glycogenosis, Type IB; Argininemia; Pyruvate Kinase Deficiency; Pyruvate Carboxylase Deficiency; Amino Sugar Metabolism; The Oncogenic Action of Fumarate; 3-Phosphoglycerate Dehydrogenase Deficiency; Glycolysis; Non-Ketotic Hyperglycinemia; 2-Hydroxyglutric Aciduria (D and L Form); Glucose-Alanine Cycle; G(M2)-Gangliosidosis: Variant B, Tay-Sachs Disease; Alanine Metabolism; Hyperglycinemia, Non-Ketotic; Cystinosis, Ocular Nonnephropathic; Dimethylglycine Dehydrogenase Deficiency; Glycogenosis, Type VII. Tarui Disease; Dihydropyrimidine Dehydrogenase Deficiency (DHPD); Lactic Acidemia; Homocarnosinosis; Primary Hyperoxaluria Type I; Ornithine Transcarbamylase Deficiency (OTC Deficiency); The Oncogenic Action of L-2-Hydroxyglutarate in Hydroxygluaricaciduria; Sarcosinemia; Urea Cycle; Phosphoenolpyruvate Carboxykinase Deficiency 1 (PEPCK1); Cysteine Metabolism |
| PharmGKB | PA164778686 |
| ChEMBL | CHEMBL1162144 |
