| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10014061 | HBV | ENSG00000079215.15 | protein_coding | SLC1A3 | No | No | 6507 | A0A087WT87 A0A087X0U3 P43003 Q7Z5T0 Q8N169 |
| TVIS10044297 | HBV | ENSG00000079215.15 | protein_coding | SLC1A3 | No | No | 6507 | A0A087WT87 A0A087X0U3 P43003 Q7Z5T0 Q8N169 |
| TVIS10044298 | HBV | ENSG00000079215.15 | protein_coding | SLC1A3 | No | No | 6507 | A0A087WT87 A0A087X0U3 P43003 Q7Z5T0 Q8N169 |
| TVIS20010139 | HPV | ENSG00000079215.15 | protein_coding | SLC1A3 | No | No | 6507 | A0A087WT87 A0A087X0U3 P43003 Q7Z5T0 Q8N169 |
| TVIS20034512 | HPV | ENSG00000079215.15 | protein_coding | SLC1A3 | No | No | 6507 | A0A087WT87 A0A087X0U3 P43003 Q7Z5T0 Q8N169 |
| TVIS20045277 | HPV | ENSG00000079215.15 | protein_coding | SLC1A3 | No | No | 6507 | A0A087WT87 A0A087X0U3 P43003 Q7Z5T0 Q8N169 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | SLC1A3 |
|---|---|
| DrugBank ID | DB00142 |
| Drug Name | Glutamic acid |
| Target ID | BE0001115 |
| UniProt ID | P43003 |
| Regulation Type | |
| PubMed IDs | 16855093; 17088867; 16959378 |
| Citations | Glowatzki E, Cheng N, Hiel H, Yi E, Tanaka K, Ellis-Davies GC, Rothstein JD, Bergles DE: The glutamate-aspartate transporter GLAST mediates glutamate uptake at inner hair cell afferent synapses in the mammalian cochlea. J Neurosci. 2006 Jul 19;26(29):7659-64.@@Beart PM, O'Shea RD: Transporters for L-glutamate: an update on their molecular pharmacology and pathological involvement. Br J Pharmacol. 2007 Jan;150(1):5-17. Epub 2006 Nov 6.@@Nickell J, Salvatore MF, Pomerleau F, Apparsundaram S, Gerhardt GA: Reduced plasma membrane surface expression of GLAST mediates decreased glutamate regulation in the aged striatum. Neurobiol Aging. 2007 Nov;28(11):1737-48. Epub 2006 Sep 7. |
| Groups | Approved; Nutraceutical |
| Direct Classification | Glutamic acid and derivatives |
| SMILES | N[C@@H](CCC(O)=O)C(O)=O |
| Pathways | Histidinemia; Guanidinoacetate Methyltransferase Deficiency (GAMT Deficiency); 3-Methylglutaconic Aciduria Type I; beta-Ketothiolase Deficiency; Purine Nucleoside Phosphorylase Deficiency; Tyrosine Metabolism; Ketoprofen Action Pathway; Glutamate Metabolism; Argininosuccinic Aciduria; Salla Disease/Infantile Sialic Acid Storage Disease; Tyrosinemia Type I; Hyperinsulinism-Hyperammonemia Syndrome; 2-Methyl-3-hydroxybutryl-CoA Dehydrogenase Deficiency; Glutaric Aciduria Type I; Propanoate Metabolism; Celecoxib Action Pathway; Glycine and Serine Metabolism; Suprofen Action Pathway; Indomethacin Action Pathway; Carbamoyl Phosphate Synthetase Deficiency; Sialuria or French Type Sialuria; Ibuprofen Action Pathway; Saccharopinuria/Hyperlysinemia II; Histidine Metabolism; Arginine and Proline Metabolism; Purine Metabolism; Diflunisal Action Pathway; Etodolac Action Pathway; Ammonia Recycling |
| PharmGKB | PA449776 |
| ChEMBL | CHEMBL575060 |
