| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30082552 | HIV | ENSG00000115902.11 | protein_coding | SLC1A4 | No | No | 6509 | P43007 |
| TVIS30050486 | HIV | ENSG00000115902.11 | protein_coding | SLC1A4 | No | No | 6509 | P43007 |
| TVIS30050487 | HIV | ENSG00000115902.11 | protein_coding | SLC1A4 | No | No | 6509 | P43007 |
| TVIS30050488 | HIV | ENSG00000115902.11 | protein_coding | SLC1A4 | No | No | 6509 | P43007 |
| TVIS30050489 | HIV | ENSG00000115902.11 | protein_coding | SLC1A4 | No | No | 6509 | P43007 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | SLC1A4 |
|---|---|
| DrugBank ID | DB00160 |
| Drug Name | Alanine |
| Target ID | BE0000480 |
| UniProt ID | P43007 |
| Regulation Type | |
| PubMed IDs | 17311416; 17510490; 17237199; 17475673; 17195090 |
| Citations | Zhang Z, Papageorgiou G, Corrie JE, Grewer C: Pre-steady-state currents in neutral amino acid transporters induced by photolysis of a new caged alanine derivative. Biochemistry. 2007 Mar 27;46(12):3872-80. Epub 2007 Feb 21.@@Takasaki C, Miura E, Watanabe M: Segmental and complementary expression of L-serine biosynthetic enzyme 3-phosphoglycerate dehydrogenase and neutral amino acid transporter ASCT1 in the mouse kidney. Biomed Res. 2007 Apr;28(2):61-9.@@Zhang Z, Grewer C: The sodium-coupled neutral amino acid transporter SNAT2 mediates an anion leak conductance that is differentially inhibited by transported substrates. Biophys J. 2007 Apr 1;92(7):2621-32. Epub 2007 Jan 19.@@Pinho MJ, Pinto V, Serrao MP, Jose PA, Soares-da-Silva P: Underexpression of the Na+-dependent neutral amino acid transporter ASCT2 in the spontaneously hypertensive rat kidney. Am J Physiol Regul Integr Comp Physiol. 2007 Jul;293(1):R538-47. Epub 2007 May 2.@@Wu Y, Shen D, Chen Z, Clayton S, Vadgama JV: Taxol induced apoptosis regulates amino acid transport in breast cancer cells. Apoptosis. 2007 Mar;12(3):593-612. Epub 2006 Dec 29. |
| Groups | Nutraceutical |
| Direct Classification | Alanine and derivatives |
| SMILES | C[C@H](N)C(O)=O |
| Pathways | gamma-Glutamyltranspeptidase Deficiency; Clomocycline Action Pathway; Josamycin Action Pathway; Gentamicin Action Pathway; Kanamycin Action Pathway; 5-Oxoprolinuria; Azithromycin Action Pathway; Glutamate Metabolism; Clindamycin Action Pathway; Clarithromycin Action Pathway; Argininosuccinic Aciduria; Hyperinsulinism-Hyperammonemia Syndrome; Tryptophan Metabolism; Alanine Metabolism; Glutaminolysis and Cancer; Glycine and Serine Metabolism; Troleandomycin Action Pathway; Dimethylglycine Dehydrogenase Deficiency; Selenoamino Acid Metabolism; Oxytetracycline Action Pathway; Tetracycline Action Pathway; Carbamoyl Phosphate Synthetase Deficiency; Erythromycin Action Pathway; Netilmicin Action Pathway; Dihydropyrimidine Dehydrogenase Deficiency (DHPD); Glutathione Metabolism; Neomycin Action Pathway; Roxithromycin Action Pathway; Arbekacin Action Pathway; Streptomycin Action Pathway |
| PharmGKB | PA448055 |
| ChEMBL | CHEMBL279597 |
