Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS30013510HIVENSG00000164638.11protein_codingSLC29A4NoNo222962Q7RTT9
TVIS20012976HPVENSG00000164638.11protein_codingSLC29A4NoNo222962Q7RTT9
TVIS20012975HPVENSG00000164638.11protein_codingSLC29A4NoNo222962Q7RTT9
TVIS20020929HPVENSG00000164638.11protein_codingSLC29A4NoNo222962Q7RTT9
TVIS20061523HPVENSG00000164638.11protein_codingSLC29A4NoNo222962Q7RTT9
TVIS20033045HPVENSG00000164638.11protein_codingSLC29A4NoNo222962Q7RTT9
TCGA Plot Options
Drug Information
GeneSLC29A4
DrugBank IDDB01104
Drug NameSertraline
Target IDBE0004775
UniProt IDQ7RTT9
Regulation Type
PubMed IDs19022290; 17046718; 20012264
CitationsDaws LC: Unfaithful neurotransmitter transporters: focus on serotonin uptake and implications for antidepressant efficacy. Pharmacol Ther. 2009 Jan;121(1):89-99. doi: 10.1016/j.pharmthera.2008.10.004. Epub 2008 Oct 29.@@Zhou M, Engel K, Wang J: Evidence for significant contribution of a newly identified monoamine transporter (PMAT) to serotonin uptake in the human brain. Biochem Pharmacol. 2007 Jan 1;73(1):147-54. doi: 10.1016/j.bcp.2006.09.008. Epub 2006 Sep 14.@@Haenisch B, Bonisch H: Interaction of the human plasma membrane monoamine transporter (hPMAT) with antidepressants and antipsychotics. Naunyn Schmiedebergs Arch Pharmacol. 2010 Jan;381(1):33-9. doi: 10.1007/s00210-009-0479-8. Epub 2009 Dec 10.
GroupsApproved
Direct ClassificationTametralines
SMILESCN[C@H]1CC[C@@H](C2=CC(Cl)=C(Cl)C=C2)C2=CC=CC=C12
Pathways
PharmGKBPA451333
ChEMBLCHEMBL809