| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS44026763 | HTLV-1 | ENSG00000010379.16 | protein_coding | SLC6A13 | No | No | 6540 | Q9NSD5 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | SLC6A13 |
|---|---|
| DrugBank ID | DB08848 |
| Drug Name | Guvacine |
| Target ID | BE0004776 |
| UniProt ID | Q9NSD5 |
| Regulation Type | inhibitor |
| PubMed IDs | 458448; 10903390; 20512624 |
| Citations | Schousboe A, Thorbek P, Hertz L, Krogsgaard-Larsen P: Effects of GABA analogues of restricted conformation on GABA transport in astrocytes and brain cortex slices and on GABA receptor binding. J Neurochem. 1979 Jul;33(1):181-9.@@Krogsgaard-Larsen P, Frolund B, Frydenvang K: GABA uptake inhibitors. Design, molecular pharmacology and therapeutic aspects. Curr Pharm Des. 2000 Aug;6(12):1193-209.@@Sunol C, Babot Z, Cristofol R, Sonnewald U, Waagepetersen HS, Schousboe A: A possible role of the non-GAT1 GABA transporters in transfer of GABA from GABAergic to glutamatergic neurons in mouse cerebellar neuronal cultures. Neurochem Res. 2010 Sep;35(9):1384-90. doi: 10.1007/s11064-010-0196-1. Epub 2010 May 30. |
| Groups | Experimental |
| Direct Classification | Alkaloids and derivatives |
| SMILES | OC(=O)C1=CCCNC1 |
| Pathways | |
| PharmGKB | |
| ChEMBL | CHEMBL76768 |
