Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS20030137HPVENSG00000103546.19protein_codingSLC6A2NoNo6530P23975
TCGA Plot Options
Drug Information
GeneSLC6A2
DrugBank IDDB00182
Drug NameAmphetamine
Target IDBE0000486
UniProt IDP23975
Regulation Typeagonist
PubMed IDs12954796; 7700252
CitationsRothman RB, Vu N, Partilla JS, Roth BL, Hufeisen SJ, Compton-Toth BA, Birkes J, Young R, Glennon RA: In vitro characterization of ephedrine-related stereoisomers at biogenic amine transporters and the receptorome reveals selective actions as norepinephrine transporter substrates. J Pharmacol Exp Ther. 2003 Oct;307(1):138-45. Epub 2003 Sep 3.@@Wall SC, Gu H, Rudnick G: Biogenic amine flux mediated by cloned transporters stably expressed in cultured cell lines: amphetamine specificity for inhibition and efflux. Mol Pharmacol. 1995 Mar;47(3):544-50.
GroupsApproved; Illicit; Investigational
Direct ClassificationAmphetamines and derivatives
SMILESCC(N)CC1=CC=CC=C1
Pathways
PharmGKBPA448408
ChEMBLCHEMBL405