| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30035946 | HIV | ENSG00000092068.21 | protein_coding | SLC7A8 | No | No | 23428 | Q9UHI5 |
| TVIS20009427 | HPV | ENSG00000092068.21 | protein_coding | SLC7A8 | No | No | 23428 | Q9UHI5 |
| TVIS20051813 | HPV | ENSG00000092068.21 | protein_coding | SLC7A8 | No | No | 23428 | Q9UHI5 |
| TVIS44047238 | HTLV-1 | ENSG00000092068.21 | protein_coding | SLC7A8 | No | No | 23428 | Q9UHI5 |
| TVIS44047237 | HTLV-1 | ENSG00000092068.21 | protein_coding | SLC7A8 | No | No | 23428 | Q9UHI5 |
| TVIS44041748 | HTLV-1 | ENSG00000092068.21 | protein_coding | SLC7A8 | No | No | 23428 | Q9UHI5 |
| TVIS44047115 | HTLV-1 | ENSG00000092068.21 | protein_coding | SLC7A8 | No | No | 23428 | Q9UHI5 |
| TVIS44047236 | HTLV-1 | ENSG00000092068.21 | protein_coding | SLC7A8 | No | No | 23428 | Q9UHI5 |
Target Gene Table
▼
TCGA Plot Options
▼
Drug Information
▼
| Gene | SLC7A8 |
|---|---|
| DrugBank ID | DB00120 |
| Drug Name | Phenylalanine |
| Target ID | BE0000789 |
| UniProt ID | Q9UHI5 |
| Regulation Type | |
| PubMed IDs | 12101005; 10574970; 12930836; 9349567; 12498902 |
| Citations | Shennan DB, Calvert DT, Travers MT, Kudo Y, Boyd CA: A study of L-leucine, L-phenylalanine and L-alanine transport in the perfused rat mammary gland: possible involvement of LAT1 and LAT2. Biochim Biophys Acta. 2002 Aug 19;1564(1):133-9.@@Rossier G, Meier C, Bauch C, Summa V, Sordat B, Verrey F, Kuhn LC: LAT2, a new basolateral 4F2hc/CD98-associated amino acid transporter of kidney and intestine. J Biol Chem. 1999 Dec 3;274(49):34948-54.@@Babu E, Kanai Y, Chairoungdua A, Kim DK, Iribe Y, Tangtrongsup S, Jutabha P, Li Y, Ahmed N, Sakamoto S, Anzai N, Nagamori S, Endou H: Identification of a novel system L amino acid transporter structurally distinct from heterodimeric amino acid transporters. J Biol Chem. 2003 Oct 31;278(44):43838-45. Epub 2003 Aug 20.@@Satoh S, Kimura T, Toda M, Maekawa M, Ono S, Narita H, Miyazaki H, Murayama T, Nomura Y: Involvement of L-type-like amino acid transporters in S-nitrosocysteine-stimulated noradrenaline release in the rat hippocampus. J Neurochem. 1997 Nov;69(5):2197-205.@@Nemoto T, Shimma N, Horie S, Saito T, Okuma Y, Nomura Y, Murayama T: Involvement of the system L amino acid transporter on uptake of S-nitroso-L-cysteine, an endogenous S-nitrosothiol, in PC12 cells. Eur J Pharmacol. 2003 Jan 1;458(1-2):17-24. |
| Groups | Approved; Investigational; Nutraceutical |
| Direct Classification | Phenylalanine and derivatives |
| SMILES | N[C@@H](CC1=CC=CC=C1)C(O)=O |
| Pathways | Phenylalanine and Tyrosine Metabolism; Tyrosinemia Type 2 (or Richner-Hanhart Syndrome); Tyrosinemia Type 3 (TYRO3); Phenylketonuria |
| PharmGKB | PA450931 |
| ChEMBL | CHEMBL301523 |
