| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS30067938 | HIV | ENSG00000128602.11 | protein_coding | SMO | Yes | No | 6608 | Q99835 |
| TVIS20068475 | HPV | ENSG00000128602.11 | protein_coding | SMO | Yes | No | 6608 | Q99835 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | SMO |
|---|---|
| DrugBank ID | DB01047 |
| Drug Name | Fluocinonide |
| Target ID | BE0004659 |
| UniProt ID | Q99835 |
| Regulation Type | agonist |
| PubMed IDs | 20439738 |
| Citations | Wang J, Lu J, Bond MC, Chen M, Ren XR, Lyerly HK, Barak LS, Chen W: Identification of select glucocorticoids as Smoothened agonists: potential utility for regenerative medicine. Proc Natl Acad Sci U S A. 2010 May 18;107(20):9323-8. doi: 10.1073/pnas.0910712107. Epub 2010 May 3. |
| Groups | Approved; Investigational |
| Direct Classification | Gluco/mineralocorticoids, progestogins and derivatives |
| SMILES | [H][C@@]12C[C@@]3([H])[C@]4([H])C[C@H](F)C5=CC(=O)C=C[C@]5(C)[C@@]4(F)[C@@H](O)C[C@]3(C)[C@@]1(OC(C)(C)O2)C(=O)COC(C)=O |
| Pathways | |
| PharmGKB | PA449664 |
| ChEMBL | CHEMBL1501 |
