Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10032406HBVENSG00000132639.15protein_codingSNAP25NoNo6616P60880
TVIS20012490HPVENSG00000132639.15protein_codingSNAP25NoNo6616P60880
TVIS20055826HPVENSG00000132639.15protein_codingSNAP25NoNo6616P60880
TVIS20055621HPVENSG00000132639.15protein_codingSNAP25NoNo6616P60880
TVIS44011195HTLV-1ENSG00000132639.15protein_codingSNAP25NoNo6616P60880
TCGA Plot Options
Drug Information
GeneSNAP25
DrugBank IDDB00083
Drug NameBotulinum toxin type A
Target IDBE0000390
UniProt IDP60880
Regulation Typeinhibitor
PubMed IDs14644446; 15222581; 16831062; 9886085
CitationsZhou JY, Wang ZF, Ren XM, Tang MZ, Shi YL: Antagonism of botulinum toxin type A-induced cleavage of SNAP-25 in rat cerebral synaptosome by toosendanin. FEBS Lett. 2003 Dec 4;555(2):375-9.@@Flynn TC: Myobloc. Dermatol Clin. 2004 Apr;22(2):207-11, vii.@@Straughan D: Progress in applying the Three Rs to the potency testing of Botulinum toxin type A. Altern Lab Anim. 2006 Jun;34(3):305-13.@@Vaidyanathan VV, Yoshino K, Jahnz M, Dorries C, Bade S, Nauenburg S, Niemann H, Binz T: Proteolysis of SNAP-25 isoforms by botulinum neurotoxin types A, C, and E: domains and amino acid residues controlling the formation of enzyme-substrate complexes and cleavage. J Neurochem. 1999 Jan;72(1):327-37. doi: 10.1046/j.1471-4159.1999.0720327.x.
GroupsApproved; Investigational
Direct ClassificationPeptides
SMILES
Pathways
PharmGKBPA164754825
ChEMBL