| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10019883 | HBV | ENSG00000140263.15 | protein_coding | SORD | No | No | 6652 | Q00796 |
| TVIS10007558 | HBV | ENSG00000140263.15 | protein_coding | SORD | No | No | 6652 | Q00796 |
| TVIS20012583 | HPV | ENSG00000140263.15 | protein_coding | SORD | No | No | 6652 | Q00796 |
| TVIS20015709 | HPV | ENSG00000140263.15 | protein_coding | SORD | No | No | 6652 | Q00796 |
| TVIS20015562 | HPV | ENSG00000140263.15 | protein_coding | SORD | No | No | 6652 | Q00796 |
| TVIS44023692 | HTLV-1 | ENSG00000140263.15 | protein_coding | SORD | No | No | 6652 | Q00796 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | SORD |
|---|---|
| DrugBank ID | DB00157 |
| Drug Name | NADH |
| Target ID | BE0000299 |
| UniProt ID | Q00796 |
| Regulation Type | |
| PubMed IDs | 17508915; 17343568 |
| Citations | Ido Y: Pyridine nucleotide redox abnormalities in diabetes. Antioxid Redox Signal. 2007 Jul;9(7):931-42.@@Klimacek M, Hellmer H, Nidetzky B: Catalytic mechanism of Zn2+-dependent polyol dehydrogenases: kinetic comparison of sheep liver sorbitol dehydrogenase with wild-type and Glu154-->Cys forms of yeast xylitol dehydrogenase. Biochem J. 2007 Jun 15;404(3):421-9. |
| Groups | Approved; Nutraceutical |
| Direct Classification | (5'->5')-dinucleotides |
| SMILES | NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@](O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O |
| Pathways | Ethylmalonic Encephalopathy; 3-Methylglutaconic Aciduria Type III; Short-Chain Acyl-CoA Dehydrogenase Deficiency (SCAD Deficiency); Caffeine Metabolism; Fructose and Mannose Degradation; Isovaleric Aciduria; Lysine Degradation; Methylmalonic Aciduria Due to Cobalamin-Related Disorders; Glycerol Phosphate Shuttle; Zellweger Syndrome; Propionic Acidemia; Glycolysis; Xanthine Dehydrogenase Deficiency (Xanthinuria); S-Adenosylhomocysteine (SAH) Hydrolase Deficiency; Tryptophan Metabolism; Glutaric Aciduria Type I; 3-Methylcrotonyl-CoA Carboxylase Deficiency Type I; Glycine N-Methyltransferase Deficiency; Dimethylglycine Dehydrogenase Deficiency; Androgen and Estrogen Metabolism; Nucleotide Sugars Metabolism; 3-Methylglutaconic Aciduria Type IV; Dihydropyrimidine Dehydrogenase Deficiency (DHPD); Malate-Aspartate Shuttle; Folate Metabolism; Valine, Leucine, and Isoleucine Degradation; Maple Syrup Urine Disease; Glycerol Kinase Deficiency; Adenylosuccinate Lyase Deficiency; Cysteine Metabolism |
| PharmGKB | PA164755085 |
| ChEMBL | CHEMBL1234616 |
