| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS20068509 | HPV | ENSG00000145545.13 | protein_coding | SRD5A1 | No | No | 6715 | P18405 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | SRD5A1 |
|---|---|
| DrugBank ID | DB00367 |
| Drug Name | Levonorgestrel |
| Target ID | BE0000539 |
| UniProt ID | P18405 |
| Regulation Type | inhibitor |
| PubMed IDs | 11075290; 1828548 |
| Citations | Rabe T, Kowald A, Ortmann J, Rehberger-Schneider S: Inhibition of skin 5 alpha-reductase by oral contraceptive progestins in vitro. Gynecol Endocrinol. 2000 Aug;14(4):223-30.@@Cassidenti DL, Paulson RJ, Serafini P, Stanczyk FZ, Lobo RA: Effects of sex steroids on skin 5 alpha-reductase activity in vitro. Obstet Gynecol. 1991 Jul;78(1):103-7. |
| Groups | Approved; Investigational |
| Direct Classification | Estrogens and derivatives |
| SMILES | [H][C@@]12CC[C@@](O)(C#C)[C@@]1(CC)CC[C@]1([H])[C@@]3([H])CCC(=O)C=C3CC[C@@]21[H] |
| Pathways | |
| PharmGKB | PA450218 |
| ChEMBL | CHEMBL1389 |
