Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS10018917HBVENSG00000130413.16protein_codingSTK33NoNo65975B4DDH2
F8WAK5
Q9BYT3
TVIS10012207HBVENSG00000130413.16protein_codingSTK33NoNo65975B4DDH2
F8WAK5
Q9BYT3
TVIS10038692HBVENSG00000130413.16protein_codingSTK33NoNo65975B4DDH2
F8WAK5
Q9BYT3
TVIS10046874HBVENSG00000130413.16protein_codingSTK33NoNo65975B4DDH2
F8WAK5
Q9BYT3
TVIS10050488HBVENSG00000130413.16protein_codingSTK33NoNo65975B4DDH2
F8WAK5
Q9BYT3
TVIS30074163HIVENSG00000130413.16protein_codingSTK33NoNo65975B4DDH2
F8WAK5
Q9BYT3
TVIS20049387HPVENSG00000130413.16protein_codingSTK33NoNo65975B4DDH2
F8WAK5
Q9BYT3
TVIS20018471HPVENSG00000130413.16protein_codingSTK33NoNo65975B4DDH2
F8WAK5
Q9BYT3
TVIS44017410HTLV-1ENSG00000130413.16protein_codingSTK33NoNo65975B4DDH2
F8WAK5
Q9BYT3
TVIS44034365HTLV-1ENSG00000130413.16protein_codingSTK33NoNo65975B4DDH2
F8WAK5
Q9BYT3
TCGA Plot Options
Drug Information
GeneSTK33
DrugBank IDDB12010
Drug NameFostamatinib
Target IDBE0009386
UniProt IDQ9BYT3
Regulation Typeinhibitor
PubMed IDs26516587
CitationsRolf MG, Curwen JO, Veldman-Jones M, Eberlein C, Wang J, Harmer A, Hellawell CJ, Braddock M: In vitro pharmacological profiling of R406 identifies molecular targets underlying the clinical effects of fostamatinib. Pharmacol Res Perspect. 2015 Oct;3(5):e00175. doi: 10.1002/prp2.175. Epub 2015 Sep 4.
GroupsApproved; Investigational
Direct ClassificationMethoxyanilines
SMILESCOC1=CC(NC2=NC=C(F)C(NC3=NC4=C(OC(C)(C)C(=O)N4COP(O)(O)=O)C=C3)=N2)=CC(OC)=C1OC
Pathways
PharmGKB
ChEMBLCHEMBL2103830