Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS44022085HTLV-1ENSG00000198829.6protein_codingSUCNR1NoNo56670Q9BXA5
TCGA Plot Options
Drug Information
GeneSUCNR1
DrugBank IDDB00139
Drug NameSuccinic acid
Target IDBE0002258
UniProt IDQ9BXA5
Regulation Type
PubMed IDs17192395
CitationsMacaulay IC, Tijssen MR, Thijssen-Timmer DC, Gusnanto A, Steward M, Burns P, Langford CF, Ellis PD, Dudbridge F, Zwaginga JJ, Watkins NA, van der Schoot CE, Ouwehand WH: Comparative gene expression profiling of in vitro differentiated megakaryocytes and erythroblasts identifies novel activatory and inhibitory platelet membrane proteins. Blood. 2007 Apr 15;109(8):3260-9. Epub 2006 Dec 27.
GroupsApproved; Nutraceutical
Direct ClassificationDicarboxylic acids and derivatives
SMILESOC(=O)CCC(O)=O
PathwaysMitochondrial Complex II Deficiency; 3-Methylglutaconic Aciduria Type III; 2-Ketoglutarate Dehydrogenase Complex Deficiency; 4-Hydroxybutyric Aciduria/Succinic Semialdehyde Dehydrogenase Deficiency; Oxidation of Branched-Chain Fatty Acids; Isovaleric Aciduria; Warburg Effect; Refsum Disease; Isobutyryl-CoA Dehydrogenase Deficiency; Propionic Acidemia; 2-Hydroxyglutric Aciduria (D and L Form); Hyperornithinemia-Hyperammonemia-Homocitrullinuria [HHH-syndrome]; 3-Methylcrotonyl-CoA Carboxylase Deficiency Type I; Congenital Lactic Acidosis; 3-Hydroxy-3-methylglutaryl-CoA Lyase Deficiency; Fumarase Deficiency; Succinic Semialdehyde Dehydrogenase Deficiency; Arginine: Glycine Amidinotransferase Deficiency (AGAT Deficiency); Prolidase Deficiency (PD); Creatine Deficiency, Guanidinoacetate Methyltransferase Deficiency; Methylmalonic Aciduria; 3-Methylglutaconic Aciduria Type IV; Ornithine Aminotransferase Deficiency (OAT Deficiency); Ketone Body Metabolism; Homocarnosinosis; Methylmalonate Semialdehyde Dehydrogenase Deficiency; Prolinemia Type II; The Oncogenic Action of 2-Hydroxyglutarate; Valine, Leucine, and Isoleucine Degradation; Maple Syrup Urine Disease
PharmGKBPA164747739
ChEMBLCHEMBL576