Target Gene Table
VIS IDVirusEnsembl IDGene TypeTarget GeneOncogeneTumor Suppressor GeneNCBI IDUniprot ID
TVIS30079080HIVENSG00000169836.5protein_codingTACR3NoNo6870P29371
TVIS30060720HIVENSG00000169836.5protein_codingTACR3NoNo6870P29371
TVIS20033534HPVENSG00000169836.5protein_codingTACR3NoNo6870P29371
TVIS20058844HPVENSG00000169836.5protein_codingTACR3NoNo6870P29371
TVIS20057902HPVENSG00000169836.5protein_codingTACR3NoNo6870P29371
TVIS44008558HTLV-1ENSG00000169836.5protein_codingTACR3NoNo6870P29371
TCGA Plot Options
Drug Information
GeneTACR3
DrugBank IDDB04872
Drug NameOsanetant
Target IDBE0002371
UniProt IDP29371
Regulation Type
PubMed IDs17172464
CitationsTian G, Wilkins D, Scott CW: Neurokinin-3 receptor-specific antagonists talnetant and osanetant show distinct mode of action in cellular Ca2+ mobilization but display similar binding kinetics and identical mechanism of binding in ligand cross-competition. Mol Pharmacol. 2007 Mar;71(3):902-11. Epub 2006 Dec 15.
GroupsInvestigational
Direct Classification1-benzoylpiperidines
SMILESCN(C(C)=O)C1(CCN(CCC[C@@]2(CCCN(C2)C(=O)C2=CC=CC=C2)C2=CC(Cl)=C(Cl)C=C2)CC1)C1=CC=CC=C1
Pathways
PharmGKB
ChEMBLCHEMBL346178