| VIS ID | Virus | Ensembl ID | Gene Type | Target Gene | Oncogene | Tumor Suppressor Gene | NCBI ID | Uniprot ID |
|---|---|---|---|---|---|---|---|---|
| TVIS10014382 | HBV | ENSG00000003436.16 | protein_coding | TFPI | No | No | 7035 | P10646 |
| TVIS10019145 | HBV | ENSG00000003436.16 | protein_coding | TFPI | No | No | 7035 | P10646 |
| TVIS10045291 | HBV | ENSG00000003436.16 | protein_coding | TFPI | No | No | 7035 | P10646 |
| TVIS10049970 | HBV | ENSG00000003436.16 | protein_coding | TFPI | No | No | 7035 | P10646 |
| TVIS30080079 | HIV | ENSG00000003436.16 | protein_coding | TFPI | No | No | 7035 | P10646 |
| TVIS30051951 | HIV | ENSG00000003436.16 | protein_coding | TFPI | No | No | 7035 | P10646 |
| TVIS30051952 | HIV | ENSG00000003436.16 | protein_coding | TFPI | No | No | 7035 | P10646 |
| TVIS20055081 | HPV | ENSG00000003436.16 | protein_coding | TFPI | No | No | 7035 | P10646 |
| TVIS20033920 | HPV | ENSG00000003436.16 | protein_coding | TFPI | No | No | 7035 | P10646 |
| TVIS20055153 | HPV | ENSG00000003436.16 | protein_coding | TFPI | No | No | 7035 | P10646 |
Target Gene Table
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TCGA Plot Options
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Drug Information
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| Gene | TFPI |
|---|---|
| DrugBank ID | DB00036 |
| Drug Name | Coagulation factor VIIa Recombinant Human |
| Target ID | BE0000967 |
| UniProt ID | P10646 |
| Regulation Type | |
| PubMed IDs | 11772005; 7559599; 8700900; 12974870; 11238112 |
| Citations | Mine S, Yamazaki T, Miyata T, Hara S, Kato H: Structural mechanism for heparin-binding of the third Kunitz domain of human tissue factor pathway inhibitor. Biochemistry. 2002 Jan 8;41(1):78-85.@@Narita M, Bu G, Olins GM, Higuchi DA, Herz J, Broze GJ Jr, Schwartz AL: Two receptor systems are involved in the plasma clearance of tissue factor pathway inhibitor in vivo. J Biol Chem. 1995 Oct 20;270(42):24800-4.@@Stassens P, Bergum PW, Gansemans Y, Jespers L, Laroche Y, Huang S, Maki S, Messens J, Lauwereys M, Cappello M, Hotez PJ, Lasters I, Vlasuk GP: Anticoagulant repertoire of the hookworm Ancylostoma caninum. Proc Natl Acad Sci U S A. 1996 Mar 5;93(5):2149-54.@@Lee AY, Vlasuk GP: Recombinant nematode anticoagulant protein c2 and other inhibitors targeting blood coagulation factor VIIa/tissue factor. J Intern Med. 2003 Oct;254(4):313-21.@@Hansen CB, Pyke C, Petersen LC, Rao LV: Tissue factor-mediated endocytosis, recycling, and degradation of factor VIIa by a clathrin-independent mechanism not requiring the cytoplasmic domain of tissue factor. Blood. 2001 Mar 15;97(6):1712-20. |
| Groups | Approved |
| Direct Classification | Peptides |
| SMILES | |
| Pathways | |
| PharmGKB | PA164748389 |
| ChEMBL |
